Evidence map›Paper›PMID 34013991›Full record

ArticleJournal of clinical apheresis2021

Exogenous insulin antibody syndrome treated with plasma exchange after an incomplete response to immunosuppressive therapy.

Yuan Zhuang, Xudong Wei, Yang Yu, Deqing Wang

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of clinical apheresis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuan ZhuangDepartment of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-8521-5032
Xudong WeiDepartment of Endocrinology, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yang YuDepartment of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Deqing WangDepartment of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 43-year-old man with a 23-year history of type II diabetes presented with uncontrolled hyperglycemia with frequent episodes of ketoacidosis. He was diagnosed with exogenous insulin antibody syndrome, and received high-dose methylprednisolone to treat insulin resistance. Ketoacidosis relapsed 2 years later, and the patient showed an incomplete response to glucocorticoids. We decided to administer therapeutic plasma exchange, which resulted in rapid lowering of the daily insulin requirement and improved glycemic control.

Indexed as

AdultAntibodiesDiabetes Mellitus, Type 2HumansHyperglycemiaImmunosuppression TherapyImmunosuppressive AgentsInsulinInsulin ResistanceMalePlasma ExchangePlasmapheresisPrevalenceSyndromeAntibodiesImmunosuppressive AgentsInsulindiabetesexogenous insulin antibody syndromehyperglycemiatherapeutic plasma exchange

Identifiers

PMID34013991
PMCPMC8453898
OpenAlexW3160149065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.