Evidence map›Paper›PMID 34013807›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Metabolic MRI with hyperpolarized [1-

Nikolaj Bøgh, Rie B Olin, Esben Ss Hansen, Jeremy W Gordon, Sabrina K Bech, Lotte B Bertelsen, Juan D Sánchez-Heredia, Jakob U Blicher, Leif Østergaard, Jan H Ardenkjær-Larsen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Three-dimensional high-resolution TMagnetic resonance in medicine · 2025
    Article
  3. Article
  4. [Research Progress in Applying HyperpolarizedSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  5. Current methods for hyperpolarized [1-Magnetic resonance in medicine · 2024
    Review
  6. Article
  7. Volumetric Patch-Based Super-Resolution Reconstruction of HyperpolarizedIEEE access : practical innovations, open solutions · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Initial Experience on Hyperpolarized [1-Tomography (Ann Arbor, Mich.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Nikolaj BøghThe MR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-0321-3269
Rie B OlinDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Esben Ss HansenThe MR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Jeremy W GordonDepartment of Radiology and Biomedical Imaging, University of California San Francisco, CA, USA.ORCID 0000-0003-2760-4886
Sabrina K BechThe MR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Lotte B BertelsenThe MR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Juan D Sánchez-HerediaDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Jakob U BlicherDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Leif ØstergaardCenter of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark.
Jan H Ardenkjær-LarsenDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Robert A BokDepartment of Radiology and Biomedical Imaging, University of California San Francisco, CA, USA.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California San Francisco, CA, USA.
Christoffer LaustsenThe MR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Aarhus University · DKTechnical University of Denmark · DKUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute ischemic stroke patients benefit from reperfusion in a short time-window after debut. Later treatment may be indicated if viable brain tissue is demonstrated and this outweighs the inherent risks of late reperfusion. Magnetic resonance imaging (MRI) with hyperpolarized [1-

Indexed as

AnimalsBrainBrain InfarctionCase-Control StudiesCerebrovascular CirculationEndothelin-1FemaleHumansIschemic StrokeMagnetic Resonance ImagingModels, AnimalPerfusion ImagingPyruvic AcidReperfusionSwineEndothelin-1Pyruvic AcidLactatemetabolismMRIneuroradiologypenumbrastroke

Identifiers

PMID34013807
PMCPMC8756460
OpenAlexW3161984404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.