Evidence map›Paper›PMID 34013797›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Kinetics and 28-day test-retest repeatability and reproducibility of [

Hayel Tuncel, Ronald Boellaard, Emma M Coomans, Erik Fj de Vries, Andor Wjm Glaudemans, Paula Kopschina Feltes, David V García, Sander Cj Verfaillie, Emma E Wolters, Steven P Sweeney and 10 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
  2. Article
  3. Noninvasive Quantification of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  4. Article
  5. Synaptic changes in psychiatric and neurological disorders: state-of-the art of in vivo imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  6. Article
  7. Longitudinal Synaptic Loss in Primary Tauopathies: An In Vivo [Movement disorders : official journal of the Movement Disorder Society · 2023
    Observational
  8. Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Hayel TuncelDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Ronald BoellaardDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Emma M CoomansDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Erik Fj de VriesDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-6915-1590
Andor Wjm GlaudemansDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-8081-0641
Paula Kopschina FeltesDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center, University of Groningen, Groningen, The Netherlands.
David V GarcíaDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-3308-3167
Sander Cj VerfaillieDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Emma E WoltersDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Steven P SweeneyRodin Therapeutics Inc., Cambridge, MA, USA.
J Michael RyanRodin Therapeutics Inc., Cambridge, MA, USA.
Magnus IvarssonRodin Therapeutics Inc., Cambridge, MA, USA.
Berkley A LynchRodin Therapeutics Inc., Cambridge, MA, USA.
Patrick SchoberDepartment of Anaesthesiology, Amsterdam UMC, Amsterdam, The Netherlands.
Philip ScheltensDepartment of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Robert C SchuitDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Albert D WindhorstDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Peter P De DeynDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Bart Nm van BerckelDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Sandeep Sv GollaDepartment of Radiology & Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, The Netherlands.
Amsterdam Neuroscience · NLUniversity Medical Center Groningen · NLRodin Therapeutics (United States) · USAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[

Indexed as

AgedAged, 80 and overAlzheimer DiseaseFemaleHumansImage Interpretation, Computer-AssistedKineticsMaleMembrane GlycoproteinsMiddle AgedNerve Tissue ProteinsNeuroimagingPositron-Emission TomographyPyridinesPyrrolidinonesRadiopharmaceuticals1-((3-(methylpyridin-4-yl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-oneMembrane GlycoproteinsNerve Tissue ProteinsPyridinesPyrrolidinonesRadiopharmaceuticalsSV2A protein, human[11C]UCB-JAlzheimer’s diseasekinetic modellingPETSV2A

Identifiers

PMID34013797
PMCPMC8138337
OpenAlexW3092530164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.