Evidence map›Paper›PMID 34013785›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Biomarkers of Thrombo-Inflammatory Responses in Pulmonary Embolism Patients With Pre-Existing Versus New-Onset Atrial Fibrillation.

Dimpi Patel, Amir Darki, Debra Hoppensteadt, Iman Darwish, Mushabbar Syed, Yevgeniy Brailovsky, Jawed Fareed

Open access · goldAbstract read
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Extracellular Vesicles and Thrombogenicity in Atrial Fibrillation.International journal of molecular sciences · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dimpi Patel2456Loyola University of Chicago, Stritch School of Medicine, Maywood, IL, USA.ORCID https://orcid.org/0000-0003-4378-3589
Amir DarkiDepartment of Cardiology, 25815Loyola University Medical Center, Maywood, IL, USA.ORCID https://orcid.org/0000-0003-0144-1804
Debra HoppensteadtHemostasis and Thrombosis Laboratories, Center of Translational Research and Education, Maywood, IL, USA.ORCID https://orcid.org/0000-0001-9342-4213
Iman DarwishHemostasis and Thrombosis Laboratories, Center of Translational Research and Education, Maywood, IL, USA.
Mushabbar SyedDepartment of Cardiology, 25815Loyola University Medical Center, Maywood, IL, USA.
Yevgeniy Brailovskyepartment of Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-4811-5267
Jawed FareedHemostasis and Thrombosis Laboratories, Center of Translational Research and Education, Maywood, IL, USA.ORCID https://orcid.org/0000-0003-3465-2499
Loyola University Medical Center · USLoyola University Chicago · USThomas Jefferson University Hospital · US

Funding

Basic and Clinical Research Training for Medical StudentsT35HL120835 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZELEZNIK-LE, NANCY J · 2015 to 2024
$628k
Summer Research Experience for Medical Students in Inflammation and Infectious DiseasesT35AI125220 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI Edward M. Campbell, Simon Kaja · 2017 to 2026
$510k
NHLBI NIH HHS T35 HL120835NIAID NIH HHS T35 AI125220
6 · The paper itself

Abstract

Pulmonary embolism (PE) patients have an increased prevalence and incidence of atrial fibrillation (AF). Because comorbid AF increases risk of morbidity and mortality, we sought to investigate the role of thrombo-inflammatory biomarkers in risk stratifying patients who experience an acute PE episode. Study participants were enrolled from a Pulmonary Embolism Response Team (PERT) registry between March 2016 and March 2019 at Loyola University Medical Center and Gottlieb Memorial Hospital. This cohort was divided into 3 groups: PE patients with a prior diagnosis of AF (n = 8), PE patients with a subsequent diagnosis of AF (n = 11), and PE patients who do not develop AF (n = 71). D-dimer, CRP, PAI-1, TAFIa, FXIIIa, A2A, MP, and TFPI were profiled using the ELISA method. All biomarkers were significantly different between controls and PE patients (

Indexed as

AgedAtrial FibrillationBiomarkersFemaleHumansInflammationMaleMiddle AgedPulmonary EmbolismRetrospective StudiesRisk FactorsThrombosisBiomarkersatrial fibrillationbiomarkerspulmonary embolismthrombo-inflammation

Identifiers

PMID34013785
PMCPMC8142239
OpenAlexW3162136020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.