ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2021
Not all that glitters is COVID-19: a case series demonstrating the need for histopathology when skin findings accompany SARS-CoV-2 infection.
Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Cutaneous Manifestation in COVID-19: A Lesson Over 2 Years Into the Pandemic.Clinical medicine & research · 2023Review
- Review
- Paucity of cutaneous manifestations of COVID-19 among inpatients at a referral hospital in India.JAAD international · 2022Article
- Pityrosporum folliculitis in critically ill COVID-19 patients.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022Article
- SARS-CoV-2 Infection and Vaccination Cutaneous Manifestations for the Inpatient Dermatologist.Current dermatology reports · 2022Review
- The crucial role of clinicopathological correlation in COVID-19-related cutaneous manifestations.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDescriptions of cutaneous findings associated with COVID-19 have not been consistently accompanied by histopathology or confirmatory testing for SARS-CoV-2.
objectiveTo describe and classify the cutaneous findings with supporting histopathology of confirmed COVID-19 inpatients.
methodsWe included consecutive inpatients with a confirmed diagnosis of COVID-19 for whom a dermatology consult was requested. A skin biopsy was performed in all cases. Skin findings were classified as being compatible with a cutaneous manifestation of COVID-19 or as representing a distinct clinical entity.
resultsTwenty-eight patients were studied in whom thirty-one dermatologic diagnoses were made. Twenty-two of the dermatoses were compatible with a cutaneous manifestation of COVID-19; nine entities were not associated with infection by SARS-CoV-2. The most common COVID-19-associated pattern was an exanthematous presentation. In four patients, a new pattern was observed, characterized by discrete papules with varied histopathological findings including a case of neutrophilic eccrine hidradenitis. No cases of pernio-like lesions were identified. Skin findings not associated with COVID-19 represented 29% of diagnoses and included Malassezia folliculitis, tinea, miliaria and contact dermatitis. LIMITATIONS: There is no gold-standard test to distinguish between viral exanthems and drug reactions.
conclusionA histopathological study is critical before attributing skin findings to a manifestation of COVID-19.
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