ArticleThe Journal of comparative neurology2021
A causal role for the pulvinar in coordinating task-independent cortico-cortical interactions.
Article in The Journal of comparative neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Article
- Causal role for pulvinar burst firing in thalamo-cortical attention control.bioRxiv : the preprint server for biology · 2025Article
- Convergent effects of different anesthetics on changes in phase alignment of cortical oscillations.Cell reports · 2025Article
- A model of thalamo-cortical interaction for incremental binding in mental contour-tracing.PLoS computational biology · 2025Article
- Article
- Attentional modulation of secondary somatosensory and visual thalamus of mice.bioRxiv : the preprint server for biology · 2024Article
- Transthalamic Pathways for Cortical Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Attentional selection and communication through coherence: Scope and limitations.PLoS computational biology · 2024Article
- Causal oscillations in the visual thalamo-cortical network in sustained attention in ferrets.Current biology : CB · 2024Article
- The Associative Thalamus: A Switchboard for Cortical Operations and a Promising Target for Schizophrenia.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- Patterns of longitudinal subcortical atrophy over one year in amnestic mild cognitive impairment and its impact on cognitive performance: a preliminary study.Turkish journal of medical sciences · 2024Article
- High-Resolution Tractography Protocol to Investigate the Pathways between Human Mediodorsal Thalamic Nucleus and Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The perceptual consequences and neurophysiology of eye blinks.Frontiers in systems neuroscience · 2023Review
- The thalamus in psychosis spectrum disorder.Frontiers in neuroscience · 2023Article
- Computational components of visual predictive coding circuitry.Frontiers in neural circuits · 2023Review
- Relay and higher-order thalamic nuclei show an intertwined functional association with cortical-networks.Communications biology · 2022Article
- Attention control in the primate brain.Current opinion in neurobiology · 2022Review
- Dynamic pulvino-cortical interactions in the primate attention network.Current opinion in neurobiology · 2020Review
- Muscimol-induced inactivation of the ventral prefrontal cortex impairs counting performance in rhesus monkeys.Science progressArticle
Corrections and comments
- Erratum issuedErratum.2022
Authors and funding
3 authors.
Funding
Abstract
The pulvinar is the largest nucleus in the primate thalamus and has topographically organized connections with multiple cortical areas, thereby forming extensive cortico-pulvino-cortical input-output loops. Neurophysiological studies have suggested a role for these transthalamic pathways in regulating information transmission between cortical areas. However, evidence for a causal role of the pulvinar in regulating cortico-cortical interactions is sparse and it is not known whether pulvinar's influences on cortical networks are task-dependent or, alternatively, reflect more basic large-scale network properties that maintain functional connectivity across networks regardless of active task demands. In the current study, under passive viewing conditions, we conducted simultaneous electrophysiological recordings from ventral (area V4) and dorsal (lateral intraparietal area [LIP]) nodes of macaque visual system, while reversibly inactivating the dorsal part of the lateral pulvinar (dPL), which shares common anatomical connectivity with V4 and LIP, to probe a causal role of the pulvinar. Our results show a significant reduction in local field potential phase coherence between LIP and V4 in low frequencies (4-15 Hz) following muscimol injection into dPL. At the local level, no significant changes in firing rates or LFP power were observed in LIP or in V4 following dPL inactivation. Synchronization between pulvinar spikes and cortical LFP phase decreased in low frequencies (4-15 Hz) both in LIP and V4, while the low frequency synchronization between LIP spikes and pulvinar phase increased. These results indicate a causal role for pulvinar in synchronizing neural activity between interconnected cortical nodes of a large-scale network, even in the absence of an active task state.
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