Evidence map›Paper›PMID 34013459›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021

The ASA score predicts infections, cardiovascular complications, and hospital readmissions after hip fracture - A nationwide cohort study.

A C Meyer, H Eklund, M Hedström, K Modig

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 5 of them syntheses that pooled it.

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52citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  8. Efficacy of low-dose Escherichia coli-derived recombinant human bone morphogenetic protein-2 in minimally invasive transforaminal lumbar interbody fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

A C MeyerUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, SE-17177, Stockholm, Sweden. anna.meyer@ki.se.ORCID http://orcid.org/0000-0003-2749-7179
H EklundUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, SE-17177, Stockholm, Sweden.
M HedströmDepartment of Clinical Science, Intervention and Technology (CLINTEC) Karolinska Institutet, SE-17177, Stockholm, Sweden.
K ModigUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, SE-17177, Stockholm, Sweden.

Funding

Åke Wiberg Stiftelse M18-005Familjen Kamprads Stiftelse 2019135Stockholms Läns Landsting 2019 Med
6 · The paper itself

Abstract

This study examines the association between the ASA physical status classification score at hip fracture surgery and severe postoperative complications in patients aged 60 and older. Among both men and women, ASA scores consistently predict a wide range of complications including infections, cardiovascular complications, hospital readmissions, and death.

introductionHip fractures are common in aging populations and associated with poor prognosis. This study examines how the American Society of Anaesthesiologists (ASA) physical status classification is related to severe complications among hip fracture patients including infections, cardiovascular diseases, hospital readmissions, and death.

methodsBased on a linkage of the Swedish National Inpatient Register with the Swedish National Registry for Hip Fractures (RIKSHÖFT), this study includes patients aged 60+ with first hip fracture between 1998 and 2017. We estimated associations between ASA score and complications during the hospital stay and during 1 year after hip fracture using multivariable-adjusted logistic regression and Cox proportional hazard regression.

resultsThe study population included 170,193 hip fracture patients of which 24% died and 39% were readmitted to hospital within 1 year. The most common complications were urinary tract infections, pneumonia, second hip fractures, and heart failure. Among both men and women, higher ASA scores were consistently associated with higher risks for all complications included in this study. The strongest associations were observed for heart failure, myocardial infarction, pneumonia, and death.

conclusionASA scores are routinely assessed in clinical practice and predict a wide range of postoperative complications among hip fracture patients. Since many complications may be preventable through adequate drug treatment, rehabilitation, and risk awareness, future studies should examine the mechanisms linking ASA scores to complication risk in order to improve preventive strategies. Particularly, the high risk of cardiovascular complications among patients with high ASA scores deserves clinical and scientific attention.

Indexed as

Cardiovascular InfectionsHip FracturesAgedCohort StudiesFemaleHumansMaleMiddle AgedPatient ReadmissionPostoperative ComplicationsRetrospective StudiesRisk FactorsASA scoreComorbidityComplicationsHip fracturePrognosisReadmission

Identifiers

PMID34013459
PMCPMC8563539

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.