Evidence map›Paper›PMID 34013183›Full record

ArticleInternational Journal of Cardiology. Hypertension2021

Association of family history with incidence and gestational hypertension outcomes of preeclampsia.

Chia-Tung Wu, Chang-Fu Kuo, Chia-Pin Lin, Yu-Tung Huang, Shao-Wei Chen, Hsien-Ming Wu, Pao-Hsien Chu

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Article in International Journal of Cardiology. Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chia-Tung WuDepartment of Cardiology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan City, Taiwan, ROC.
Chang-Fu KuoAllergy and Immunology, Center for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan City, Taiwan, ROC.
Chia-Pin LinDepartment of Cardiology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan City, Taiwan, ROC.
Yu-Tung HuangCenter for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan City, Taiwan, ROC.
Shao-Wei ChenCenter for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan City, Taiwan, ROC.
Hsien-Ming WuDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University School of Medicine, Taoyuan, Taiwan, ROC.
Pao-Hsien ChuDepartment of Cardiology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan City, Taiwan, ROC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational hypertension and preeclampsia are hypertensive disorders related to pregnancy that can cause maternal morbidity and fetal growth retardation. The association of these disorders with family history remains unclear.

objectivesTo examine the degree of family aggregation of preeclampsia and gestational hypertension in Taiwan.

methodsThe study was conducted using the data from the National Health Insurance Database of Taiwan. Delivery events in Taiwan from 1999 to 2013 were collected. Preeclampsia was identified based on the hospital diagnosis of index delivery. The family aggregation pattern of preeclampsia was assessed and analyzed using the relationship registered in the database with the patients.

resultsA total of 60,314 preeclampsia events were identified among 4,091,641 deliveries, accounting for 1.5% of the cohort. The incidence of preeclampsia increased with maternal age. A total of 768 preeclampsia events occurred in mothers who had a sororal history of preeclampsia (n = 20,704), accounting for 1.3% of all preeclampsia events (n = 60,314). Mothers who had a sororal history of preeclampsia had a relative risk (RR) of 2.6 (95% confidence interval [CI]: 2.41-2.80) for preeclampsia compared with mothers who did not have a sororal history of preeclampsia. The RR for gestational hypertension was 2.79 (95% CI: 2.36-3.3) in mothers with a positive sororal history of gestational hypertension.

conclusionsHaving a sororal history of preeclampsia was a strong risk factor for preeclampsia and gestational hypertension in mothers in Taiwan. The pattern of family aggregation was similar at all maternal ages.

Indexed as

Cardiovascular eventsCI, confidence intervalEnvironmentalFamily aggregationGestational hypertensionHereditaryICD-9-CM, International Classification of DiseasesNHI, National Health Insurance NHINHIRD, National Health Insurance Research DatabaseNinth Revision, Clinical ModificationPre-eclampsiaRR, relative riskSD, standardized difference

Identifiers

PMID34013183
PMCPMC8113806

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.