Evidence map›Paper›PMID 34013174›Full record

ArticleiScience2021

Enhancing the chondrogenic potential of chondrogenic progenitor cells by deleting RAB5C.

Jerome Nicolas Janssen, Valerio Izzi, Elvira Henze, Gökhan Cingöz, Florian Lowen, David Küttner, Ruth Neumann, Christof Lenz, Vicki Rosen, Nicolai Miosge

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Jerome Nicolas JanssenTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
Valerio IzziFaculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland.
Elvira HenzeTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
Gökhan CingözTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
Florian LowenTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
David KüttnerTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
Ruth NeumannTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
Christof LenzBioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Vicki RosenDevelopmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.
Nicolai MiosgeTissue Regeneration Work Group, Department of Prosthodontics, Medical Faculty, Georg-August-University, 37075 Göttingen, Germany.
University of Göttingen · DEHarvard University · USMax Planck Institute for Biophysical Chemistry · DEUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is the most prevalent chronic joint disease that affects a large proportion of the elderly population. Chondrogenic progenitor cells (CPCs) reside in late-stage OA cartilage tissue, producing a fibrocartilaginous extracellular matrix; these cells can be manipulated

Indexed as

OmicsProteomicsStem cells researchTranscriptomics

Identifiers

PMID34013174
PMCPMC8113995
OpenAlexW3158974882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.