Evidence map›Paper›PMID 34013069›Full record

ArticleHealth science reports2021

Effect of antioxidant, malondialdehyde, macro-mineral, and trace element serum concentrations in Bangladeshi patients with schizophrenia: A case-control study.

S M Naim Uddin, Farhana Sultana, Md Giash Uddin, Syed Masudur Rahman Dewan, Mohammed Kamrul Hossain, Mohammad Safiqul Islam

Abstract read
In one paragraph

Article in Health science reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Zinc in psychosis (Review).Molecular medicine reports · 2025
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S M Naim UddinDepartment of Pharmacy Faculty of Biological Sciences, University of Chittagong Chittagong Bangladesh.ORCID https://orcid.org/0000-0003-4511-8697
Farhana SultanaDepartment of Pharmacy Noakhali Science and Technology University Noakhali Bangladesh.
Md Giash UddinDepartment of Pharmacy Faculty of Biological Sciences, University of Chittagong Chittagong Bangladesh.ORCID https://orcid.org/0000-0003-0792-0902
Syed Masudur Rahman DewanDepartment of Pharmacy Noakhali Science and Technology University Noakhali Bangladesh.ORCID https://orcid.org/0000-0003-1443-7150
Mohammed Kamrul HossainDepartment of Pharmacy Faculty of Biological Sciences, University of Chittagong Chittagong Bangladesh.
Mohammad Safiqul IslamDepartment of Pharmacy Noakhali Science and Technology University Noakhali Bangladesh.ORCID https://orcid.org/0000-0003-4924-5319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSchizophrenia (SCZ) is an incurable neuropsychiatric disorder generally described by impaired social behavior and altered recognition of reality. For the first time, this study explored serum levels of antioxidants (vitamin A, E, and C), malondialdehyde (MDA), macro-minerals (calcium, potassium, and sodium), and trace elements (zinc, iron, and selenium) in Bangladeshi patients with SCZ and thereby, discovering any pathophysiological correlation.

methodsThis case-controlled study evaluated 63 patients with SCZ as cases and 63 healthy individuals as controls. Vitamin A and E levels were defined by RP-HPLC. MDA and vitamin C levels were measured by using UV spectrophotometry, and macro and trace elements by atomic absorption spectroscopy.

resultsThis study found significantly (

conclusionsThe findings connect that the pathogenesis of SCZ may have a correlation with altered levels of antioxidants, MDA, macro-minerals, and trace elements.

Indexed as

antioxidantlipid peroxidationmacro‐mineralsschizophreniatrace element

Identifiers

PMID34013069
PMCPMC8112814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.