Evidence map›Paper›PMID 34013058›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2021

Clinical characteristics and risk factors of gastroesophageal reflux disease in Vietnamese patients with upper gastrointestinal symptoms undergoing esophagogastroduodenoscopy.

Duc T Quach, Quyen T T Pham, Truc L T Tran, Nhu T H Vu, Quang D Le, Doan T N Nguyen, Ngoc L B Dang, Huy M Le, Nhan Q Le

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05353933 (Efficacy and Safety of Thread Embedding Acupuncture Combined With PPI in Treating GERD), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05353933 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Thread Embedding Acupuncture Combined With PPI in Treating GERD

TypeinterventionalSponsorUniversity of Medicine and Pharmacy at Ho Chi Minh CityRan2022 to 2022Enrolled66ConditionsGastroesophageal RefluxArmsThread embedding acupuncture, Pantoprazole 40mg
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Duc T QuachDepartment of Internal Medicine University of Medicine and Pharmacy at Hochiminh City Ho Chi Minh Vietnam.ORCID https://orcid.org/0000-0003-0141-921X
Quyen T T PhamDepartment of Gastroenterology Cho-Ray Hospital Ho Chi Minh Vietnam.
Truc L T TranDepartment of Endoscopy University Medical Center Ho Chi Minh Vietnam.
Nhu T H VuDepartment of Internal Medicine University of Medicine and Pharmacy at Hochiminh City Ho Chi Minh Vietnam.
Quang D LeDepartment of Internal Medicine University of Medicine and Pharmacy at Hochiminh City Ho Chi Minh Vietnam.
Doan T N NguyenDepartment of Internal Medicine University of Medicine and Pharmacy at Hochiminh City Ho Chi Minh Vietnam.
Ngoc L B DangDepartment of Endoscopy University Medical Center Ho Chi Minh Vietnam.
Huy M LeDepartment of Endoscopy University Medical Center Ho Chi Minh Vietnam.
Nhan Q LeDepartment of Endoscopy University Medical Center Ho Chi Minh Vietnam.
University of Medicine and Pharmacy at Ho Chi Minh City · VNUniversity Medical Center HCMC · VNCho Ray Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe risk factors associated with the increase in prevalence of gastroesophageal reflux disease (GERD) are not consistent across countries and there have been few studies in Asia in the past 10 years. This study was conducted to assess the features and risk factors of GERD in Vietnamese patients.

methodsA cross-sectional study was conducted on 1947 out-patients ≥18 years of age who were presented with upper gastrointestinal symptoms and underwent esophagogastroduodenoscopy. Reflux esophagitis was graded according to the Los Angeles classification. Endoscopically suspected Barrett's esophagus (BE) was recorded according to the Prague C and M criteria and biopsy was taken for histologic examination.

resultsThere were 511 (26.2%) patients with GERD, 242 (47.4%) with nonerosive reflux disease, and 269 (52.6%) with reflux esophagitis and/or BE. Epigastric pain, regurgitation, and heartburn were the chief complaints in 36.8%, 27.0%, and 9.2% of patients, respectively. Most of the patients with mucosal injury had reflux esophagitis in mild grade and BE in the form of C0M ≤2 (99.6%, 231/232 and 97.8%, 46/47, respectively). In multivariate analysis, hiatal hernia, male gender, waist-to-hip ratio (independent from general obesity), and smoking were risk factors for GERD while

conclusionsThe majority of GERD patients had none or mild mucosal injury. Typical reflux symptoms, however, may not be the chief complaints. Central obesity would be more important than general obesity as a risk factor, while

Indexed as

Barrett's esophagusgastroesophageal reflux diseaseHelicobacter pylorireflux esophagitisrisk factorsVietnam

Identifiers

PMID34013058
PMCPMC8114995
OpenAlexW3144433051

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.