Evidence map›Paper›PMID 34013042›Full record

ArticleOpen medicine (Warsaw, Poland)2021

circAGFG1 sponges miR-28-5p to promote non-small-cell lung cancer progression through modulating HIF-1α level.

Xiaoan Ma, Cuijie Wang, Juan Chen, Dan Wei, Fei Yu, Juan Sun

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  16. Effects of hsa-miR-28-5p on Adriamycin Sensitivity in Diffuse Large B-Cell Lymphoma.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoan MaDepartment of Respiratory Medicine, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000, Shannxi, China.
Cuijie WangDepartment of Respiratory Medicine, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000, Shannxi, China.
Juan ChenDepartment of Respiratory Medicine, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000, Shannxi, China.
Dan WeiDepartment of Respiratory Medicine, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000, Shannxi, China.
Fei YuDepartment of Respiratory Medicine, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000, Shannxi, China.
Juan SunDepartment of Respiratory Medicine, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang 712000, Shannxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) have gained much attention for their crucial regulatory roles in human diseases and cancers. However, the role and the mechanism of circRNA ArfGAP with FG repeats 1 (circAGFG1) in non-small-cell lung cancer (NSCLC) are still largely unknown. circAGFG1 was highly expressed in NSCLC, and high expression of circAGFG1 was closely related to the low survival rate of NSCLC patients. circAGFG1 knockdown inhibited the proliferation, migration, and invasion and promoted the apoptosis of NSCLC cells. circAGFG1 bound to miR-28-5p in NSCLC cells, and circAGFG1 promoted NSCLC progression partly through sponging miR-28-5p

Indexed as

circAGFG1glycolysisHIF-1αmiR-28-5pNSCLC

Identifiers

PMID34013042
PMCPMC8111482

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.