Evidence map›Paper›PMID 34012970›Full record

ArticleFrontiers in medicine2021

Mortality and Life-Sustaining Therapy Decisions in Patients With Cancer and Acute Respiratory Failure Due to COVID-19 or Other Causes: An Observational Study.

Renato Scarsi Testa, Ana Paula Agnolon Praça, Antonio Paulo Nassar Junior, Pauliane Vieira Santana, Valdelis Novis Okamoto, Ramon Teixeira Costa, Pedro Caruso

Abstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renato Scarsi TestaIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.
Ana Paula Agnolon PraçaIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.
Antonio Paulo Nassar JuniorIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.
Pauliane Vieira SantanaIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.
Valdelis Novis OkamotoIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.
Ramon Teixeira CostaIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.
Pedro CarusoIntensive Care Unit, Antonio Cândido (AC) Camargo Cancer Center, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is unknown if patients with cancer and acute respiratory failure due to COVID-19 have different clinical or cancer-related characteristics, decisions to forgo life-sustaining therapies (LST), and mortality compared to patients with cancer and acute respiratory failure due to other causes. In a cohort study, we tested the hypothesis that COVID-19 was associated with increased in-hospital mortality and decreased decisions to forgo LST in patients with cancer and acute respiratory failure. We employed two multivariate logistic regression models. Propensity score matching was employed as sensitivity analysis. We compared 382 patients without COVID-19 with 65 with COVID-19. Patients with COVID-19 had better performance status, less metastatic tumors, and progressive cancer. In-hospital mortality of patients with COVID-19 was lower compared with patients without COVID-19 (46.2 vs. 74.6%;

Indexed as

cancerCOVID-19critical care outcomesintensive care unitrespiratory insufficiency

Identifiers

PMID34012970
PMCPMC8126609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.