Evidence map›Paper›PMID 34012945›Full record

ArticleAnnals of surgical treatment and research2021

Comparing postoperative pain in various pressure pneumoperitoneum of laparoscopic cholecystectomy: a double-blind randomized controlled study.

Wonbin Chang, Tae Yoo, Won Tae Cho, Giyuon Cho

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of surgical treatment and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05530564 (Effect of Low-pressure Pneumoperitoneum on Pain and Inflammation in Laparoscopic Cholecystectomy), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05530564 nacompletednot on this map

Effect of Low-pressure Pneumoperitoneum on Pain and Inflammation in Laparoscopic Cholecystectomy: A Prospective Randomized Clinical Trial

TypeinterventionalSponsorUniversity of JordanRan2020 to 2021Enrolled100ConditionsPneumoperitoneum, Pain, Inflammatory ResponseArmslow-pressure pneumoperitoneum, standard-pressure pneumoperitoneum
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Impact of Pneumoperitoneum Pressure on Post-Cholecystectomy Pain.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Trial
  4. Article
  5. Self-reported quality of recovery after radical prostatectomy-a prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  6. ArtiSentialAnnals of hepato-biliary-pancreatic surgery · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wonbin ChangDepartment of Surgery, Hallym University College of Medicine, Hwaseong, Korea.ORCID https://orcid.org/0000-0003-1938-5572
Tae YooDepartment of Surgery, Hallym University College of Medicine, Hwaseong, Korea.ORCID https://orcid.org/0000-0003-3834-7125
Won Tae ChoDepartment of Surgery, Hallym University College of Medicine, Hwaseong, Korea.ORCID https://orcid.org/0000-0003-3282-076X
Giyuon ChoDepartment of Surgery, Hallym University College of Medicine, Hwaseong, Korea.ORCID https://orcid.org/0000-0002-2447-5970
Hallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to evaluate the effect of different pneumoperitoneum pressures on postoperative pain, especially by subcategorizing the pressures into 3 groups during laparoscopic cholecystectomy (LC).

methodsWe conducted a prospective randomized, double-blinded study of 150 patients with benign and uncomplicated gallbladder disease. They were categorized into 3 groups. Each group (50 patients) underwent LC with different pneumoperitoneum methods: group VLP, very-low pressure (6-8 mmHg); group LP, low pressure (9-11 mmHg); and group SP, standard pressure (12-14 mmHg). The 3 groups were compared for pain intensity, duration, analgesic requirement, and complications.

resultsThe characteristics of the patients were similar among all groups. Postoperative pain scores at each time point (1, 2, 4, 6, 12, 24, and 48 hours) were not significantly different among the 3 groups. Further, operation time, hospital stay, the number of analgesic consumption doses, and postoperative complications were not significantly different among the 3 groups.

conclusionThis study demonstrates no difference in postoperative pain among various pneumoperitoneum pressures during LC. Therefore, routine use of lower-pressure pneumoperitoneum is not recommended unless in selected patients who require low-pressure pneumoperitoneum surgery.

Indexed as

Laparoscopic cholecystectomyPneumoperitoneumPostoperative pain

Identifiers

PMID34012945
PMCPMC8103153
OpenAlexW3159331545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.