Evidence map›Paper›PMID 34012926›Full record

ArticleFrontiers in cellular and infection microbiology2021

Kari E Murros, Vy A Huynh, Timo M Takala, Per E J Saris

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 2 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 2 syntheses or guidelines pooled it, 196 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
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  11. Expanding the diversity ofInternational journal of systematic and evolutionary microbiology · 2026
    Article
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  13. Review
  14. Article
  15. Article
  16. Article
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  18. Article
  19. Review
  20. Review

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kari E MurrosNeurological Outpatient Clinic of Terveystalo Healthcare, Helsinki, Finland.
Vy A HuynhDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland.
Timo M TakalaDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland.
Per E J SarisDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland.
University of Helsinki · FIEtelä-Karjalan sosiaali ja terveyspiiri · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is the most prevalent movement disorder known and predominantly affects the elderly. It is a progressive neurodegenerative disease wherein α-synuclein, a neuronal protein, aggregates to form toxic structures in nerve cells. The cause of Parkinson's disease (PD) remains unknown. Intestinal dysfunction and changes in the gut microbiota, common symptoms of PD, are evidently linked to the pathogenesis of PD. Although a multitude of studies have investigated microbial etiologies of PD, the microbial role in disease progression remains unclear. Here, we show that Gram-negative sulfate-reducing bacteria of the genus

Indexed as

DesulfovibrioNeurodegenerative DiseasesParkinson DiseaseAgedalpha-SynucleinBacteriaHumansalpha-Synucleinalpha-synuclein (α-Syn)gut Desulfovibrio bacteriahydrogen sulfidemagnetiteParkinson’s disease (PD)

Identifiers

PMID34012926
PMCPMC8126658
OpenAlexW3159676560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.