Evidence map›Paper›PMID 34012913›Full record

ArticleFrontiers in oncology2021

LncRNA PCIR Is an Oncogenic Driver

Wenhui Guo, Jingyi Li, Haobo Huang, Fangmeng Fu, Yuxiang Lin, Chuan Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Macrophage PABPC4-SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mechanisms of Long Non-Coding RNA in Breast Cancer.International journal of molecular sciences · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Wenhui GuoDepartment of Breast Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jingyi LiCollege of Integrated Traditional Chinese and Western Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Haobo HuangDepartment of Blood Transfusion, Fujian Medical University Union Hospital, Fuzhou, China.
Fangmeng FuDepartment of Breast Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Yuxiang LinDepartment of Breast Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Chuan WangDepartment of Breast Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Fujian Medical University · CNUnion Hospital · CNFujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (LncRNA) as the key regulators in all stages of tumorigenesis and metastasis. However, the underlying mechanisms are largely unknown. Here, we report a lncRNA RP11-214F16.8, which renamed Lnc-PCIR, is upregulated and higher RNA level of Lnc-PCIR was positively correlated to the poor survival of patients with triple negative breast cancer (TNBC) tissues. Lnc-PCIR overexpression significantly promoted cell proliferation, migration, and invasion

Indexed as

long non-coding RNApoly(A) binding protein cytoplasmic 4RP11-214F16.8/Lnc-PCIRTGF-beta activated kinase 1 (MAP3K7) binding protein 3TNF-α/NF-κB signaling pathway

Identifiers

PMID34012913
PMCPMC8128249
OpenAlexW3158006325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.