Evidence map›Paper›PMID 34012871›Full record

ArticleJournal of traditional and complementary medicine2021

Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of

Frederick Ayertey, Ebenezer Ofori-Attah, Stephen Antwi, Michael Amoa-Bosompem, Georgina Djameh, Nathaniel Lartey Lartey, Mistuko Ohashi, Kwadwo Asamoah Kusi, Alfred Ampomah Appiah, Regina Appiah-Opong and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Mechanisms ofVeterinary sciences · 2026
    Review
  2. Review
  3. Article
  4. Kaempferol 3-O-Rutinoside, a Flavone Derived fromMolecules (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Potential Antioxidant and Anti-Inflammatory Effects ofInternational journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Frederick AyerteyDepartment of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Accra, Ghana.
Ebenezer Ofori-AttahDepartment of Clinical Pathology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.
Stephen AntwiPharmacology, Toxicology Department, Center for Plant Medicine Research, Mampong, Akwapim, Ghana.
Michael Amoa-BosompemDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.
Georgina DjamehDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.
Nathaniel Lartey LarteyDepartment of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Accra, Ghana.
Mistuko OhashiDepartment of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.
Kwadwo Asamoah KusiDepartment of Immunology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, South Africa.
Alfred Ampomah AppiahPhytochemistry Department, Center for Plant Medicine Research, Mampong, Akwapim, Ghana.
Regina Appiah-OpongDepartment of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Accra, Ghana.
Laud Kenneth OkineDepartment of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Accra, Ghana.
University of Ghana · GHNoguchi Memorial Institute for Medical Research · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimMost developing countries resort to medicinal plants for treating diseases, but few of these have scientific backing for their use. The aim of the study was to validate traditional use of EXPERIMENTAL PROCEDURE: Effect of hydroethanolic leaf extract of RESULTS AND

conclusionNo mortalities were recorded in acute toxicity assay after administering 5000 mg/kg

Indexed as

CPM, chlorpheniramineCPMR, Centre for Plant Medicine ResearchCyclooxygenase-2CytokinesEdemaGRA, granisetronHEML, hydroethanolic Morinda lucidaInflammationNitric oxideSFN, sulforuphane

Identifiers

PMID34012871
PMCPMC8116761
OpenAlexW3047061015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.