Evidence map›Paper›PMID 34012827›Full record

ArticleTranslational pediatrics2021

The role and mechanism of 1,25-dihydroxyvitamin D

Wei-Min Tian, Wei-Wei Chen, Yu Chen, Chen-Xi Lin, Jin-Xian Huang, Ya-Ping Song, Yun-Gang Yang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Wei-Min TianDepartment of Pediatrics, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Wei-Wei ChenDepartment of Pediatrics, Affiliated Hospital of Jining Medical University, Jining, China.
Yu ChenDepartment of Pediatrics, Zhongshan Hospital of Xiamen University, Xiamen, China.
Chen-Xi LinDepartment of Pediatrics, Zhongshan Hospital of Xiamen University, Xiamen, China.
Jin-Xian HuangDepartment of Pediatrics, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Ya-Ping SongSchool of Medicine, Xiamen University, Xiamen, China.
Yun-Gang YangDepartment of Pediatrics, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Shanghai Public Health Clinical Center · CNZhongshan Hospital of Xiamen University · CNAffiliated Hospital of Jining Medical University · CNFirst Affiliated Hospital of Xiamen University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchial asthma (referred to as asthma in the present study) is the most common chronic airway inflammatory disease in childhood. The present study aimed to investigate the effect of 1,25-dihydroxyvitamin D

methodsThe acute asthma model was induced by ovalbumin (OVA) and pertussis bacillus, and ASMCs obtained from asthmatic rats were cultured

resultsThe expression of ROCK, MLC20 and P-MLC20 in each treatment group were significantly lower, when compared to the TNF group (P<0.05), but this remained stronger than (P<0.05) or similar to (P>0.05) that in the N group.

conclusionsThe regulation mechanism of 1,25-(OH)

Indexed as

1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]AsthmaeotaxinIL-8RhoVDR

Identifiers

PMID34012827
PMCPMC8107869
OpenAlexW3156352136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.