Evidence map›Paper›PMID 34012717›Full record

ReviewJournal of pathology informatics2021

Artificial Intelligence in Pathology: From Prototype to Product.

André Homeyer, Johannes Lotz, Lars Ole Schwen, Nick Weiss, Daniel Romberg, Henning Höfener, Norman Zerbe, Peter Hufnagl

Abstract readReview
In one paragraph

Review in Journal of pathology informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Prognostic factors of breast phyllodes tumors.Histology and histopathology · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Recommendations on compiling test datasets for evaluating artificial intelligence solutions in pathology.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

André HomeyerFraunhofer MEVIS, Bremen, Germany.
Johannes LotzFraunhofer MEVIS, Bremen, Germany.
Lars Ole SchwenFraunhofer MEVIS, Bremen, Germany.
Nick WeissFraunhofer MEVIS, Bremen, Germany.
Daniel RombergFraunhofer MEVIS, Bremen, Germany.
Henning HöfenerFraunhofer MEVIS, Bremen, Germany.
Norman ZerbeCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Berlin, Germany.
Peter HufnaglCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern image analysis techniques based on artificial intelligence (AI) have great potential to improve the quality and efficiency of diagnostic procedures in pathology and to detect novel biomarkers. Despite thousands of published research papers on applications of AI in pathology, hardly any research implementations have matured into commercial products for routine use. Bringing an AI solution for pathology to market poses significant technological, business, and regulatory challenges. In this paper, we provide a comprehensive overview and advice on how to meet these challenges. We outline how research prototypes can be turned into a product-ready state and integrated into the IT infrastructure of clinical laboratories. We also discuss business models for profitable AI solutions and reimbursement options for computer assistance in pathology. Moreover, we explain how to obtain regulatory approval so that AI solutions can be launched as

Indexed as

Artificial intelligencebusiness modelimage analysisintegrationpathologyregulatory approvalreimbursementtechnology readiness

Identifiers

PMID34012717
PMCPMC8112352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.