Evidence map›Paper›PMID 34012611›Full record

ReviewJournal of thoracic disease2021

Pulmonary metastasectomy in colorectal carcinoma.

Paul Beckers, Lawek Berzenji, Suresh K Yogeswaran, Patrick Lauwers, Giada Bilotta, Nikol Shkarpa, Jeroen Hendriks, Paul E Van Schil

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) randomized controlled trial: a systematic review of published responses.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2022
    Pooled it
  3. Article
  4. Article
  5. Cancer metastasisFrontiers in bioengineering and biotechnology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Paul BeckersDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Lawek BerzenjiDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Suresh K YogeswaranDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Patrick LauwersDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Giada BilottaDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Nikol ShkarpaDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Jeroen HendriksDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Paul E Van SchilDepartment of Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Belgium.
Antwerp University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. It is estimated that 50% of all patients with CRC develop metastases, most commonly in the liver and the lung. Lung metastases are seen in approximately 10-15% of all patients with CRC. A large number of these patients with metastatic CRC can only receive palliative treatment due to invasion of other organs and disseminated disease. However, a subset of these patients present with potentially resectable metastases. Pulmonary metastasectomy is considered to be a potentially curative treatment for selected patients with resectable metastatic CRC. Current data suggest that patients that undergo pulmonary metastasectomy have 5-year survival rates of approximately 40%. However, the majority of data published regarding lung metastasectomy is based on small, retrospective case series. Due to this lack of prospective data, it is still unclear which subset of patients will benefit most from curative-intent surgery. Furthermore, there is also controversy regarding which prognostic and genetic factors are related to survival outcomes and whether there is a difference between open and thoracoscopic approaches in terms of overall and disease-free survival. In this review, we aim to summarize the latest data on prognostic factors and survival outcomes after pulmonary metastasectomy in patients with metastatic CRC.

Indexed as

Colorectal cancerlungmetastasectomysurgical outcomes

Identifiers

PMID34012611
PMCPMC8107514
OpenAlexW3080237870

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.