Evidence map›Paper›PMID 34012593›Full record

ArticleJournal of thoracic disease2021

Abnormal spindle-like microcephaly-associated protein enhances cell invasion through Wnt/β-catenin-dependent regulation of epithelial-mesenchymal transition in non-small cell lung cancer cells.

Chunwei Xia, Xiaofeng Xu, Yiyan Ding, Cunjun Yu, Jianbing Qiao, Ping Liu

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chunwei XiaDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaofeng XuDepartment of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Yiyan DingDepartment of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Cunjun YuDepartment of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Jianbing QiaoDepartment of Respiratory Medicine, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Ping LiuDepartment of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer is one of the most common cancer worldwide, invasion and metastasis are still the bottleneck in the clinical setting. More diagnostic markers and drug targets need to be clarified. Therefore, we screened abnormal spindle-like microcephaly-associated protein (

methodsGene Expression Omnibus (GEO) datamining was used to identify

results

conclusions

Indexed as

Abnormal spindle-like microcephaly-associated proteinepithelial-mesenchymal transition (EMT)invasionlung cancersignaling transductionβ-catenin

Identifiers

PMID34012593
PMCPMC8107535
OpenAlexW3158523953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.