Evidence map›Paper›PMID 34012557›Full record

ArticleVirus evolution2021

Quantifying the dynamics of viral recombination during free virus and cell-to-cell transmission in HIV-1 infection.

Jesse Kreger, Josephine Garcia, Hongtao Zhang, Natalia L Komarova, Dominik Wodarz, David N Levy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virus evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Cell-cell communication: new insights and clinical implications.Signal transduction and targeted therapy · 2024
    Review
  2. Article
  3. Article
  4. Elevated HIV viral load is associated with higher recombination ratebioRxiv : the preprint server for biology · 2023
    Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jesse KregerDepartment of Mathematics, Rowland Hall, University of California, Irvine, CA 92697, USA.ORCID https://orcid.org/0000-0001-6438-171X
Josephine GarciaDepartment of Basic Science, New York University College of Dentistry, 921 Schwartz Building, 345 East 24th Street, New York, NY 10010-9403, USA.
Hongtao ZhangDepartment of Basic Science, New York University College of Dentistry, 921 Schwartz Building, 345 East 24th Street, New York, NY 10010-9403, USA.
Natalia L KomarovaDepartment of Mathematics, Rowland Hall, University of California, Irvine, CA 92697, USA.
Dominik WodarzDepartment of Mathematics, Rowland Hall, University of California, Irvine, CA 92697, USA.
David N LevyDepartment of Basic Science, New York University College of Dentistry, 921 Schwartz Building, 345 East 24th Street, New York, NY 10010-9403, USA.
New York University · USUniversity of California, Irvine · US

Funding

Establishing HIV-1 chromatin in resting T cells: Vpr, latency, and H2A.ZR01AI145753 · NIAID · NEW YORK UNIVERSITY · PI LEVY, DAVID N · 2019 to 2023
$2.0M
Viruis Dynamics and Multiple Infection of Cells: Computational and Experimental AR01AI093998 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI LEVY, DAVID N, WODARZ, DOMINIK F · 2011 to 2014
$1.5M
NIAID NIH HHS R01 AI093998NIAID NIH HHS R01 AI145753
6 · The paper itself

Abstract

Recombination has been shown to contribute to human immunodeficiency virus-1 (HIV-1) evolution

Indexed as

cell-to-cell transmissionevolutionmathematical modelsmultiplicity of infectionrecombination

Identifiers

PMID34012557
PMCPMC8117450
OpenAlexW3138705642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.