Evidence map›Paper›PMID 34012498›Full record

ArticleRadiology case reports2021

Microspheres vaginal discharge as a complication after Uterine Artery Embolization for intramural/submucosal fibroid.

Cecilia Gozzo, Giovanni Failla, Andrea Musumeci, Francesco Vacirca, Rosa Ida Romeo, Salvatore Lamberto, Pietro Valerio Foti, Antonio Cianci, Stefano Palmucci, Antonio Basile

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Update on Endovascular Therapy for Fibroids and Adenomyosis.Seminars in interventional radiology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Cecilia GozzoDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.
Giovanni FaillaDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.
Andrea MusumeciDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.
Francesco VacircaDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.
Rosa Ida RomeoStudio Iannelli - Barcellona P.G., Sicily, Italy.
Salvatore LambertoU.O. Radiodiagnostica Ospedale Patti- ASP Messina, Sicily, Italy.
Pietro Valerio FotiDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.
Antonio CianciDepartment of General Surgery and Medical-Surgery Specialities - Institute of Obstetrics and Gynecology, University of Catania, Catania, Italy.
Stefano PalmucciDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.
Antonio BasileDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I unit, University of Catania, Via Santa Sofia 78, Catania 92123, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among Uterine Artery Embolization (UAE) complications, vaginal discharge is considered very frequent, especially for submucosal fibroids. Until now, it was reported as clear odorless viscous material. To our knowledge, we describe the first report of intrauterine microsphere migration after UAE. A 45-year-old-woman was admitted to our hospital complaining metromenorrhagia, menstrual cramping, pelvic pain and dyspareunia. After a preprocedural Magnetic Resonance Imaging (MRI) study, she underwent a superselective transradial UAE using 500-700 µm and 700-900 µm microspheres with a good morphological results. At 2-month follow-up, she complained viscous vaginal discharge with "strange pink stiff sphere of about 2 mm in diameter". A post-procedural-MRI showed fibroid migration towards the uterine cavity, a frequent occurrence especially for submucosal fibroids. The microspheres transvascular migration outside the vessel wall was already reported in a study performed in sheep. Our hypothesis is that the phenomenon of transvascular migration along with the fibroid migration towards the uterine cavity after UAE, may have led the migration of the microspheres directly into the vaginal cavity causing chronic vaginal discharge with pink stiff sphere. Vaginal discharge mixed with "sphere of particles" should be included among the UAE late complication especially for intramural and/or submucosal fibroids with distance to the endometrium less than 2.4 mm at pre-procedural MRI.

Indexed as

ComplicationsMicrosphereMRIUterine artery embolizationUterine fibroidsVaginal discharge

Identifiers

PMID34012498
PMCPMC8113102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.