Evidence map›Paper›PMID 34012478›Full record

ArticleJournal of drug delivery science and technology2021

Kinetics of

V Sava, O Fihurka, A Khvorova, J Sanchez-Ramos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of drug delivery science and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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  4. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

V SavaDepartment of Neurology, University of South Florida.
O FihurkaDepartment of Neurology, University of South Florida.
A KhvorovaRNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts.
J Sanchez-RamosDepartment of Neurology, University of South Florida.

Funding

Nanocarriers Designed to Deliver Nucleic Acids to BrainR01NS095563 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI SANCHEZ-RAMOS, JUAN R · 2015 to 2019
$2.0M
Mid-Scale RNA Synthesis, Purification and Quality Control SystemS10OD020012 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KHVOROVA, ANASTASIA · 2015 to 2015
$563k
NIH HHS S10 OD020012NINDS NIH HHS R01 NS095563
6 · The paper itself

Abstract

This report describes the kinetics of Huntington's Disease (HD) gene (

Indexed as

intranasal administrationkinetics of gene loweringLowering brain HTTrepetitive dosingsiRNA loaded nanoparticles

Identifiers

PMID34012478
PMCPMC8128136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.