Evidence map›Paper›PMID 34012431›Full record

ArticleFrontiers in immunology2021

CD4

Pavla Taborska, Zuzana Strizova, Dmitry Stakheev, Ludek Sojka, Jirina Bartunkova, Daniel Smrz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Antibody-dependent enhancement of coronaviruses.International journal of biological sciences · 2025
    Review
  3. COVID-19 vaccine development: milestones, lessons and prospects.Signal transduction and targeted therapy · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pavla TaborskaDepartment of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.
Zuzana StrizovaDepartment of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.
Dmitry StakheevDepartment of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.
Ludek SojkaDepartment of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.
Jirina BartunkovaDepartment of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.
Daniel SmrzDepartment of Immunology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.
Charles University · CZUniversity Hospital in Motol · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adaptive immune response to severe acute respiratory coronavirus 2 (SARS-CoV-2) is important for vaccine development and in the recovery from coronavirus disease 2019 (COVID-19). Men and cancer patients have been reported to be at higher risks of contracting the virus and developing the more severe forms of COVID-19. Prostate cancer (PCa) may be associated with both of these risks. We show that CD4

Indexed as

Adaptive ImmunityAgedCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCoronavirus 229E, HumanCOVID-19Cross ReactionsCytokinesHumansMaleMiddle AgedProstatic NeoplasmsSARS-CoV-2Spike Glycoprotein, CoronavirusCytokinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19HCoV-229Eprostate cancerSARS-CoV-2spike glycoprotein

Identifiers

PMID34012431
PMCPMC8128251
OpenAlexW3159055469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.