Evidence map›Paper›PMID 34012404›Full record

ArticleFrontiers in physiology2021

Study of Coronary Atherosclerosis Using Blood Residence Time.

Javad Hashemi, Bhavesh Patel, Yiannis S Chatzizisis, Ghassan S Kassab

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Effect of Premature Acute Coronary Syndrome on Ocular Hemodynamics.International journal of medical sciences · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Javad HashemiCalifornia Medical Innovation Institute, San Diego, CA, United States.
Bhavesh PatelCalifornia Medical Innovation Institute, San Diego, CA, United States.
Yiannis S ChatzizisisCardiovascular Division, University of Nebraska Medical Center, Omaha, NE, United States.
Ghassan S KassabCalifornia Medical Innovation Institute, San Diego, CA, United States.
California Medical Innovations Institute · USUniversity of Nebraska Medical Center · US

Funding

Patient-Specific Simulations to Guide Coronary Bifurcation StentingR01HL144690 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CHATZIZISIS, IOANNIS S · 2019 to 2023
$3.9M
NHLBI NIH HHS R01 HL144690
6 · The paper itself

Abstract

Computational fluid dynamic-based modeling is commonly used in stenosed and stented coronary artery to characterize blood flow and identify hemodynamics factors that could lead to coronary stenosis. One such factor is the residence time (RT), which is important for investigating stenosis and restenosis progression. The current method to calculate RT, known as the relative residence time (RRT) method, does not provide the original scale of RT and only provides a relative value. We recently introduced a novel method, designated as RT method, based on developing the advection-diffusion equation with a scalar to calculate the absolute residence time. The goal of this study was to compare both methods. Our results show that both could detect regions with a high risk of stenosis and restenosis, but the RT method is also able to show the recirculation zone using pathlines in the lumen and quantify actual RT. Moreover, RT method also provided blood flow pathlines, and is correlated to wall shear stress (WSS), oscillatory shear index (OSI), RRT, and Localized Normalized Helicity (LNH) which are other critical factors to gauge stenosis severity and assess stenting in bifurcations coronary.

Indexed as

coronary artery stenosiscoronary atherosclerosisoscillatory shear indexresidence timestented bifurcationwall shear stress

Identifiers

PMID34012404
PMCPMC8128163
OpenAlexW3159351039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.