Evidence map›Paper›PMID 34012293›Full record

ArticleCancer management and research2021

Prediction of Risk Factors for Pathological Fracture After Bone Tumor Biopsy Using Finite Element Analysis.

Tadashi Iwai, Manabu Hoshi, Naoto Oebisu, Kumi Orita, Akiyoshi Shimatani, Naoki Takada, Hiroaki Nakamura

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Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tadashi IwaiDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.ORCID 0000-0001-8267-7389
Manabu HoshiDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.
Naoto OebisuDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.
Kumi OritaDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.
Akiyoshi ShimataniDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.
Naoki TakadaDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.
Hiroaki NakamuraDepartment of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to determine if finite element analysis (FEA) provides useful thresholds for bone biopsy practice patterns.

methodsThe femoral head compression test was performed on rabbit femurs, using FEA to identify the part of the bone that preferentially fractures (n=15/group). Four types of rectangular biopsy holes were made using finite element (FE) models. These models were divided into control (no defect), defect 1 (10% width), defect 2 (20% width), defect 3 (30% width), and defect 4 (40% width) groups (n=15 each). Three types of rectangular biopsy holes (defect A, 27% length; defect B, 40% length; defect C, 53% length) were also made using FE models (n=15 each). The load to failure was then predicted using FEA.

resultsAlmost all femurs with no defect were fractured at the femoral shaft in both the femoral head compression test and FEA. The experimental load to failure in intact femurs was predicted well by the FE models (R

conclusionThe FEA results correlated well with those of the femoral head compression test. A width <10% of the circumference length in bone biopsy holes helps minimize bone strength reduction using FEA. It may be useful for orthopedic doctors to perform FEA to avoid pathological fractures after bone tumor biopsy.

Indexed as

bone tumor biopsyfemurfinite element analysisNew Zealand white rabbitsorthopedics

Identifiers

PMID34012293
PMCPMC8126804

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