Evidence map›Paper›PMID 34012274›Full record

ArticleInfection and drug resistance2021

Antibacterial Effects of Disulfiram in

Tomomi Kobatake, Keiki Ogino, Hiroyuki Sakae, Kazuyoshi Gotoh, Akari Watanabe, Osamu Matsushita, Hiroyuki Okada, Kenji Yokota

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Antimicrobial Activity of N,N-Diethyldithiocarbamate againstInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. CagA and VacA inhibit gastric mucosal epithelial cell autophagy and promote the progression of gastric precancerous lesions.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  7. Article
  8. Asclepain cI, a proteolytic enzyme fromFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tomomi KobatakeGraduate School of Health Science Okayama University, Okayama, 700-8558, Japan.
Keiki OginoDepartment of Environmental Medicine, Koch Medical School, Nankoku-shi, 783-8505, Japan.
Hiroyuki SakaeDepartment of Gastroenterology and Hepatology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, 700-8558, Japan.
Kazuyoshi GotohDepartment of Bacteriology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, 700-8558, Japan.
Akari WatanabeDepartment of Oral Health Care and Rehabilitation, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, 770-8501, Japan.
Osamu MatsushitaDepartment of Bacteriology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, 700-8558, Japan.
Hiroyuki OkadaDepartment of Gastroenterology and Hepatology, Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, 700-8558, Japan.ORCID 0000-0003-2814-7146
Kenji YokotaGraduate School of Health Science Okayama University, Okayama, 700-8558, Japan.
Okayama University · JPKochi Medical School Hospital · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMATERIALS AND

methodsDrug-sensitive strains of

resultsDisulfiram suppressed the growth of 7 out of 12

conclusionDisulfiram has a bactericidal effect on

Indexed as

CagAdisulfiramHelicobacter pyloriureasevacuolating toxin

Identifiers

PMID34012274
PMCPMC8126873
OpenAlexW3163055438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.