Evidence map›Paper›PMID 34012230›Full record

ArticleMolecular vision2021

Prevalence of granular corneal dystrophy type 2-related

Jong Eun Park, Sun Ae Yun, Eun Youn Roh, Jong Hyun Yoon, Sue Shin, Chang-Seok Ki

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Molecular vision, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jong Eun ParkDepartment of Laboratory Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
Sun Ae YunCenter for Clinical Medicine, Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Korea.
Eun Youn RohDepartment of Laboratory Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Jong Hyun YoonDepartment of Laboratory Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Sue ShinDepartment of Laboratory Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Chang-Seok KiGC Genome, Yongin, Korea.
Seoul National University · KRGenome and Company (South Korea) · KRHanyang University Guri Hospital · KRSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Granular corneal dystrophy type 2 (GCD2) is an autosomal dominant disorder and is associated with the arginine to histidine substitution at codon 124 (p.R124H) of the Methods: In total, 2,060 anonymous DNA samples from a public umbilical cord blood bank were tested for the Results: Six of the 2,060 samples [0.29%; 95% confidence interval (CI), 0.12-0.67%] were heterozygous for the Conclusions: To our knowledge, this is the largest study that has estimated the prevalence of the GCD2-related

Indexed as

Asian PeoplebetaIG-H3 ProteinCorneal Dystrophies, HereditaryExtracellular Matrix ProteinsFetal BloodHumansMutationPrevalenceReal-Time Polymerase Chain ReactionRepublic of KoreaTransforming Growth Factor betabetaIG-H3 ProteinExtracellular Matrix ProteinsTransforming Growth Factor beta

Identifiers

PMID34012230
PMCPMC8116257
OpenAlexW3160309992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.