Evidence map›Paper›PMID 34012116›Full record

ArticleNature2021

Sensory neuron-derived TAFA4 promotes macrophage tissue repair functions.

Guillaume Hoeffel, Guilhaume Debroas, Anais Roger, Rafaelle Rossignol, Jordi Gouilly, Caroline Laprie, Lionel Chasson, Pierre-Vincent Barbon, Anaïs Balsamo, Ana Reynders and 2 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed
21.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 176 citations in OpenAlex.

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  13. Tenascin CNature communications · 2026
    Article
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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Guillaume Hoeffel *Aix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France. hoeffel@ciml.univ-mrs.fr.ORCID http://orcid.org/0000-0002-2534-4972
Guilhaume Debroas *Aix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Anais RogerAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.ORCID http://orcid.org/0000-0003-4872-3171
Rafaelle RossignolAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Jordi GouillyAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.ORCID http://orcid.org/0000-0001-8684-7429
Caroline LaprieAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Lionel ChassonAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Pierre-Vincent BarbonAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Anaïs BalsamoAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Ana ReyndersAix Marseille Univ., CNRS, IBDM, Institut de Biologie du Développement de Marseille, Marseille, France.
Aziz MoqrichAix Marseille Univ., CNRS, IBDM, Institut de Biologie du Développement de Marseille, Marseille, France.
Sophie UgoliniAix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France. ugolini@ciml.univ-mrs.fr.ORCID http://orcid.org/0000-0003-4041-0103
Centre National de la Recherche Scientifique · FR

Funding

European Research Council
6 · The paper itself

Abstract

Inflammation is a defence response to tissue damage that requires tight regulation in order to prevent impaired healing. Tissue-resident macrophages have a key role in tissue repair

Indexed as

RegenerationWound HealingAnimalsCell SurvivalCytokinesDisease Models, AnimalFemaleFibrosisInflammationInterleukin-10MacrophagesMembrane ProteinsMiceMice, Inbred C57BLSensory Receptor CellsSkinCytokinesInterleukin-10Membrane ProteinsTAFA4 protein, mouseTIM-4 protein, mouse

Identifiers

PMID34012116
OpenAlexW3163019925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.