Trial reportJournal of perinatology : official journal of the California Perinatal Association2021
Randomized clinical trial investigating the effect of consistent, developmentally-appropriate, and evidence-based multisensory exposures in the NICU.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Multisensory stimulation for promoting development and preventing morbidity in preterm infants.The Cochrane database of systematic reviews · 2026Pooled it
- Multisensory stimulation for promoting development and preventing morbidity in preterm infants.The Cochrane database of systematic reviews · 2026Pooled it
- Korean clinical practice guidelines for rehabilitation in critically ill patients and post-intensive care syndrome.Acute and critical care · 2026Guideline
- Eligible Infants Included in Neonatal Clinical Trials and Reasons for Noninclusion: A Systematic Review.JAMA network open · 2024Pooled it
- Race and Ethnicity of Infants Enrolled in Neonatal Clinical Trials: A Systematic Review.JAMA network open · 2023Pooled it
- Socio-demographic factors related to parent engagement in the NICU and the impact of the SENSE program.Early human development · 2021Trial
- Associations between maternal emotion dysregulation, infant negative affect and toddler mental health depend on newborn neurobehavioral profiles.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Korean Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients and Post-Intensive Care Syndrome.Annals of rehabilitation medicine · 2026Article
- Immersive physical and occupational therapy in the neonatal intensive care unit: a non-randomized comparative cohort trial protocol.Pilot and feasibility studies · 2026Article
- Newborn and family-centered care: a scoping review on related newborn rights and principles.Journal of global health · 2026Article
- Parents' Experiences With an Early Behavioral Intervention, H-HOPE, in the NICU and at Home: A Qualitative Study.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2025Article
- Description and evidence on the supporting and enhancing neonatal intensive care unit sensory experiences (SENSE) program.Acta paediatrica (Oslo, Norway : 1992) · 2025Review
- Developmental trajectories in high-risk NICU graduates during the first year of life.Early human development · 2025Article
- Enhancing Sensory Experiences for Infants Born Preterm: A Quality Improvement Project.Archives of rehabilitation research and clinical translation · 2024Review
- Multisensory stimulation for promoting development and preventing morbidity in preterm infants.The Cochrane database of systematic reviews · 2024Article
- White Matter Injury on Early-versus-Term-Equivalent Age Brain MRI in Infants Born Preterm.AJNR. American journal of neuroradiology · 2024Article
- Article
- Prenatal and perinatal factors associated with neonatal neurobehavioral profiles in the ECHO Program.Pediatric research · 2023Article
- NICU sensory experiences associated with positive outcomes: an integrative review of evidence from 2015-2020.Journal of perinatology : official journal of the California Perinatal Association · 2023Review
- Supporting and Enhancing NICU Sensory Experiences (SENSE), 2nd Edition: An Update on Developmentally Appropriate Interventions for Preterm Infants.Children (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveEvaluate the effect of a manualized multisensory program, applied across NICU hospitalization, on infant and parent outcomes. STUDY
designSeventy parent-infant dyads (born ≤32 weeks gestation) in a Level IV NICU were randomized at birth to the multisensory program or standard-of-care. Parents in the multisensory group administered prespecified amounts of age-appropriate, evidence-based sensory interventions to their infants each day during NICU hospitalization according to the Supporting and Enhancing NICU Sensory Experiences (SENSE) program.
resultsInfants who received the SENSE program had more lethargy on the NICU Network Neurobehavioral Scale (NNNS) (p = 0.05), even after controlling for medical and social risk (p = 0.043), and had higher Communication scores on the Ages and Stages Questionnaire (p = 0.04) at 1-year corrected age, but this relationship failed to reach significance after controlling for medical and social risk (p = 0.12).
conclusionThe SENSE program shows promise for improving outcomes, but more research with larger sample sizes is needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.