ArticleNature communications2021
Fast photothermal spatial light modulation for quantitative phase imaging at the nanoscale.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- White Vortex Light Generations With 7OCB Spherulite.Nanophotonics (Berlin, Germany) · 2026Article
- Reconfigurable Integrated Thermo-Optics for Aberration Correction.ACS photonics · 2024Article
- Surpassing the Diffraction Limit in Label-Free Optical Microscopy.ACS photonics · 2024Review
- Single 5-nm quantum dot detection via microtoroid optical resonator photothermal microscopy.Light, science & applications · 2024Article
- Article
- Ultrafast all-optical second harmonic wavefront shaping.Nature communications · 2024Article
- Thermal transport across membranes and the Kapitza length from photothermal microscopy.Journal of biological physics · 2023Article
- Confocal interferometric scattering microscopy reveals 3D nanoscopic structure and dynamics in live cells.Nature communications · 2023Article
- Electro-detachment of kinesin motor domain from microtubule in silico.Computational and structural biotechnology journal · 2023Article
- Optical Metasurfaces for Energy Conversion.Chemical reviews · 2022Review
- Scattering-based Light Microscopy: From Metal Nanoparticles to Single Proteins.Chemical reviews · 2021Review
- Fast photothermal spatial light modulation for quantitative phase imaging at the nanoscale.Nature communications · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spatial light modulators have become an essential tool for advanced microscopy, enabling breakthroughs in 3D, phase, and super-resolution imaging. However, continuous spatial-light modulation that is capable of capturing sub-millisecond microscopic motion without diffraction artifacts and polarization dependence is challenging. Here we present a photothermal spatial light modulator (PT-SLM) enabling fast phase imaging for nanoscopic 3D reconstruction. The PT-SLM can generate a step-like wavefront change, free of diffraction artifacts, with a high transmittance and a modulation efficiency independent of light polarization. We achieve a phase-shift > π and a response time as short as 70 µs with a theoretical limit in the sub microsecond range. We used the PT-SLM to perform quantitative phase imaging of sub-diffractional species to decipher the 3D nanoscopic displacement of microtubules and study the trajectory of a diffusive microtubule-associated protein, providing insights into the mechanism of protein navigation through a complex microtubule network.
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