ArticleScientific reports2021
Decreased vascular smooth muscle contractility in Hutchinson-Gilford Progeria Syndrome linked to defective smooth muscle myosin heavy chain expression.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- The landscape of cell regulatory and communication networks in the human dental follicle.Frontiers in bioengineering and biotechnology · 2025Article
- Aging-associated decline in vascular smooth muscle cell mechanosensation is mediated by Piezo1 channel.Aging cell · 2024Article
- Arterial Mechanics, Extracellular Matrix, and Smooth Muscle Differentiation in Carotid Arteries Deficient for Rac1.Annals of vascular medicine and research · 2024Article
- Progressive mechanical and structural changes in anterior cerebral arteries with Alzheimer's disease.Alzheimer's research & therapy · 2023Article
- Smooth muscle contribution to vaginal viscoelastic response.Journal of the mechanical behavior of biomedical materials · 2023Article
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- Progerin mislocalizes myocardin-related transcription factor in Hutchinson-Guilford Progeria syndrome.Vascular biology (Bristol, England) · 2022Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Children with Hutchinson-Gilford Progeria Syndrome (HGPS) suffer from multiple cardiovascular pathologies due to the expression of progerin, a mutant form of the nuclear envelope protein Lamin A. Progerin expression has a dramatic effect on arterial smooth muscle cells (SMCs) and results in decreased viability and increased arterial stiffness. However, very little is known about how progerin affects SMC contractility. Here, we studied the LaminA
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Registered trials
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