ArticleScientific reports2021
The antagonistic Metschnikowia andauensis produces extracellular enzymes and pulcherrimin, whose production can be promoted by the culture factors.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 26 citations in OpenAlex.
- Antagonism-driven upregulation of the pulcherriminic acid biosynthetic pathway in Metschnikowia pulcherrima and Leptosphaeria maculans interaction.World journal of microbiology & biotechnology · 2026Article
- Striking mycotoxin tolerance and zearalenone elimination capacity of the decaying wood associated yeast Sugiyamaella novakii (Trichomonascaceae).BMC microbiology · 2025Article
- Harnessing killer yeast system: from molecular insight to real world biocontrol solution.Archives of microbiology · 2025Review
- Pulcherriminic acid biosynthesis and transport: insights from a heterologous system in Saccharomyces cerevisiae.FEMS yeast research · 2025Article
- Fungal Biocontrol Agents in the Management of Postharvest Losses of Fresh Produce-A Comprehensive Review.Journal of fungi (Basel, Switzerland) · 2025Review
- Screening of highFrontiers in microbiology · 2025Article
- Two-Stage Screening ofMicroorganisms · 2024Article
- Isolation of local strains of the yeast Metschnikowia for biocontrol and lipid production purposes.World journal of microbiology & biotechnology · 2024Article
- Heterologous pulcherrimin production in Saccharomyces cerevisiae confers inhibitory activity on Botrytis conidiation.FEMS yeast research · 2024Article
- Iron Competition as an Important Mechanism of Pulcherrimin-ProducingFoods (Basel, Switzerland) · 2023Article
- Pulcherriminic acid modulates iron availability and protects against oxidative stress during microbial interactions.Nature communications · 2023Article
- Natural and engineered cyclodipeptides: Biosynthesis, chemical diversity, and engineering strategies for diversification and high-yield bioproduction.Engineering microbiology · 2023Review
- Epiphitic Microbiome of Alvarinho Wine Grapes from Different Geographic Regions in Portugal.Biology · 2023Article
- Biological Activity of Pulcherrimin from theMolecules (Basel, Switzerland) · 2022Article
- In Vitro Evaluation of Extracellular Enzyme Activity and Its Biocontrol Efficacy of Bacterial Isolates from Pepper Plants for the Management ofBioMed research international · 2022Article
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Authors and funding
9 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Biological control against microbial infections has a great potential as an alternative approach instead of fungicidal chemicals, which can cause environmental pollution. The pigment producer Metschnikowia andauensis belongs to the antagonistic yeasts, but details of the mechanism by which it inhibits growth of other microbes are less known. Our results confirmed its antagonistic capacity on other yeast species isolated from fruits or flowers and demonstrated that the antagonistic capacity was well correlated with the size of the red pigmented zone. We have isolated and characterized its red pigment, which proved to be the iron chelating pulcherrimin. Its production was possible even in the presence of 0.05 mg/ml copper sulphate, which is widely used in organic vineyards because of its antimicrobial properties. Production and localisation of the pulcherrimin strongly depended on composition of the media and other culture factors. Glucose, galactose, disaccharides and the presence of pectin or certain amino acids clearly promoted pigment production. Higher temperatures and iron concentration decreased the diameter of red pigmented zones. The effect of pH on pigment production varied depending of whether it was tested in liquid or solid media. In addition, our results suggest that other mechanisms besides the iron depletion of the culture media may contribute to the antagonistic capacity of M. andauensis.
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