Evidence map›Paper›PMID 34011649›Full record

ArticleBMJ case reports2021

COVID-19-associated central retinal vein occlusion treated with oral aspirin.

Ramesh Venkatesh, Nikitha Gurram Reddy, Sameeksha Agrawal, Arpitha Pereira

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. The spectrum of COVID-19-associated chorioretinal vasculopathy.American journal of ophthalmology case reports · 2023
    Article
  8. Retinal Changes After COVID-19 Infection and COVID-19 Vaccination.International medical case reports journal · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Observational
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ramesh VenkateshDepartment of Retina and Vitreous, Narayana Nethralaya, Bengaluru, Karnataka, India.
Nikitha Gurram ReddyDepartment of Retina and Vitreous, Narayana Nethralaya, Bengaluru, Karnataka, India.
Sameeksha AgrawalDepartment of Retina and Vitreous, Narayana Nethralaya, Bengaluru, Karnataka, India.
Arpitha PereiraOphthalmology, Betsi Cadwaladr University Health Board, Abergele, UK arpitha.pereira@wales.nhs.uk.ORCID http://orcid.org/0000-0002-3356-1256
Narayana Nethralaya · INBetsi Cadwaladr University Health Board · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a case report of central retinal vein occlusion (CRVO) associated with COVID-19 treated with oral aspirin therapy. A 56-year-old woman reported decreased vision in her left eye. Her left eye vision was 6/18, N10. Anterior segment was within normal limits. Left eye fundus was suggestive of CRVO and macular oedema. Optical coherence tomography showed cystoid macular oedema and neurosensory detachment. Blood work-up revealed elevated D-dimer levels and erythrocyte sedimentation rate (ESR). She was started on treatment with low-dose aspirin 150 mg/day. After 1 month, her vision improved to 6/6, N6. Left eye fundus showed reduced retinal haemorrhages and complete resolution of macular oedema. Her repeat blood work-up showed reduced D-dimer and ESR levels. The patient was asked to be reviewed after 3 months. This case highlights that specific treatment for reducing the hypercoagulable state caused by COVID-19 with oral aspirin therapy can result in complete resolution of CRVO macular oedema.

Indexed as

COVID-19Retinal Vein OcclusionAspirinFemaleFluorescein AngiographyHumansMiddle AgedSARS-CoV-2Tomography, Optical CoherenceAspirinCOVID-19macularetinavenous thromboembolism

Identifiers

PMID34011649
PMCPMC8137153
OpenAlexW3161653136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.