Evidence map›Paper›PMID 34011608›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Chromatin remodeler

Daniel Z Doyle, Mandy M Lam, Adel Qalieh, Yaman Qalieh, Alice Sorel, Owen H Funk, Kenneth Y Kwan

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Mild SARS-CoV-2 maternal infection in mice induces transient offspring neurodevelopmental aberrance.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Review
  5. The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Development and Evolution of Thalamocortical Connectivity.Cold Spring Harbor perspectives in biology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. mBio · 2022
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Daniel Z DoyleMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-8959-5906
Mandy M LamMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-7984-9709
Adel QaliehMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-0221-7954
Yaman QaliehMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0003-0974-9686
Alice SorelMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-7902-8986
Owen H FunkMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-6524-6958
Kenneth Y KwanMichigan Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109; kykwan@umich.edu.ORCID 0000-0003-4711-071X
University of Michigan · US

Funding

PREDOCTORAL TRAINING IN GENETICST32GM007544 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORAN, JOHN V. · 1985 to 2022
$11.3M
University of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1M
Epigenetic regulation of sequential neurogenesis and neural fate diversityR01NS097525 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KWAN, KENNETH YU-CHUNG · 2016 to 2020
$2.0M
Non-cell autonomous mechanisms of neural circuit wiring mediated by chromatin regulationF31NS110206 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DOYLE, DANIEL · 2019 to 2021
$112k
NIGMS NIH HHS R25 GM086262NIGMS NIH HHS T32 GM007544NINDS NIH HHS F31 NS110206NINDS NIH HHS R01 NS097525
6 · The paper itself

Abstract

Loss-of-function mutations in chromatin remodeler gene

Indexed as

Loss of Function MutationAbnormalities, MultipleAnimalsCerebral CortexChromatinConnectomeCorpus CallosumDNA-Binding ProteinsFaceGene DeletionGene Expression RegulationGray MatterHand Deformities, CongenitalHumansIntellectual DisabilityMiceArid1a protein, mouseChromatinDNA-Binding ProteinsTranscription Factorsaxon pathfindingcerebral cortexchromatin regulationdevelopmentneural circuits

Identifiers

PMID34011608
PMCPMC8166177
OpenAlexW3160323914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.