Evidence map›Paper›PMID 34011543›Full record

ArticleJournal of virology2021

Moloney Murine Leukemia Virus p12 Is Required for Histone Loading onto Retroviral DNAs.

Gary Z Wang, Stephen P Goff

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gary Z WangDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA.
Stephen P GoffDepartment of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, USA.
Columbia University Irving Medical Center · USHoward Hughes Medical Institute · US

Funding

Mechanisms of Silencing of Retroviral DNAs in Embryonic Cell LinesR01CA030488 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GOFF, STEPHEN PAINE · 1985 to 2024
$4.3M
Howard Hughes Medical InstituteNCI NIH HHS R01 CA030488
6 · The paper itself

Abstract

During retrovirus infection, a histone-free DNA copy of the viral RNA genome is synthesized and rapidly loaded with nucleosomes

Indexed as

CapsidCapsid ProteinsCell Line, TumorChromatinDNA, ViralGene Products, gagGenome, ViralHEK293 CellsHeLa CellsHistonesHumansMoloney murine leukemia virusVirus AssemblyCapsid ProteinsChromatinDNA, ViralGag protein p12, moloney murine leukemia virusGene Products, gagHistoneschromatin immunoprecipitationhistone loadingnuclear accumulationretroviral DNA

Identifiers

PMID34011543
PMCPMC8274600
OpenAlexW3163753443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.