ArticleJournal of immunology (Baltimore, Md. : 1950)2021
Modulating T Follicular Cells In Vivo Enhances Antigen-Specific Humoral Immunity.
Jose D Pagan, Hera Vlamakis, Anthony Gaca, Ramnik J Xavier, Robert M Anthony
Open access · bronzeAbstract read
In one paragraphArticle in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
5 authors at 2 institutions in 1 country.
Jose D PaganCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA.
Hera VlamakisBroad Immunology, Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA; and.ORCID 0000-0003-1086-9191 Anthony GacaBroad Immunology, Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA; and.ORCID 0000-0003-3476-7034 Ramnik J XavierBroad Immunology, Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA; and.
Robert M AnthonyCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA; robert.anthony@mgh.harvard.edu.ORCID 0000-0002-7283-7825 Broad Institute · USHarvard University · US
Funding
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3MThe importance of the IgG4 glycome in IgG4-related disease(s)U19AI110495 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 2014 to 2026
$7.9MExamining IgG4 sialylation as a gain of function post-translation modification in IgG4-related diseasesR01AI153441 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ANTHONY, ROBERT MCCULLOUGH, RAVETCH, JEFFREY VICTOR · 2020 to 2024
$4.1MGlycoengineering In VivoDP2AR068272 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI ANTHONY, ROBERT MCCULLOUGH · 2014 to 2014
$2.6MSIGN receptors and the antiinflammatory activity of sialylated IgG FcsK22AI091684 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ANTHONY, ROBERT MCCULLOUGH · 2012 to 2013
$270kNIAID NIH HHS K22 AI091684NIAID NIH HHS R01 AI153441NIAID NIH HHS U19 AI110495NIAMS NIH HHS DP2 AR068272NIDDK NIH HHS P30 DK043351
6 · The paper itselfAbstract
Generation of high-affinity IgG is essential for defense against infections and cancer, which is the intended consequence of many vaccines, but can cause autoimmune and inflammatory diseases when inappropriately directed against self. The interplay of T follicular helper (T
Indexed as
AnimalsAntigensImmunity, HumoralMiceMice, Inbred C57BLMice, Inbred NODMice, TransgenicT Follicular Helper CellsAntigens
Identifiers
PMID34011521
PMCPMC8164984
OpenAlexW3163895944
What OpenQuestion holds
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LicenceTDM
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