Evidence map›Paper›PMID 34011515›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2021

Inhibiting ventral hippocampal NMDA receptors and

Sherri B Briggs, Reilly Hannapel, Janavi Ramesh, Marise B Parent

Open access · diamondAbstract read
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sherri B Briggs *Neuroscience Institute, Georgia State University, Atlanta, Georgia 30303, USA.
Reilly Hannapel *Neuroscience Institute, Georgia State University, Atlanta, Georgia 30303, USA.
Janavi RameshNeuroscience Institute, Georgia State University, Atlanta, Georgia 30303, USA.
Marise B ParentNeuroscience Institute, Georgia State University, Atlanta, Georgia 30303, USA.
Georgia State University · US

Funding

Hippocampal Modulation of Energy IntakeR01DK114700 · NIDDK · GEORGIA STATE UNIVERSITY · PI PARENT, MARISE B · 2018 to 2020
$1.5M
NIDDK NIH HHS R01 DK114700
6 · The paper itself

Abstract

Research into the neural mechanisms that underlie higher-order cognitive control of eating behavior suggests that ventral hippocampal (vHC) neurons, which are critical for emotional memory, also inhibit energy intake. We showed previously that optogenetically inhibiting vHC glutamatergic neurons during the early postprandial period, when the memory of the meal would be undergoing consolidation, caused rats to eat their next meal sooner and to eat more during that next meal when the neurons were no longer inhibited. The present research determined whether manipulations known to interfere with synaptic plasticity and memory when given pretraining would increase energy intake when given prior to ingestion. Specifically, we tested the effects of blocking vHC glutamatergic N-methyl-D-aspartate receptors (NMDARs) and activity-regulated cytoskeleton-associated protein (

Indexed as

HippocampusReceptors, N-Methyl-D-AspartateAnimalsEnergy IntakeFeeding BehaviorMaleRatsRats, Sprague-DawleyReceptors, N-Methyl-D-Aspartate

Identifiers

PMID34011515
PMCPMC8139633
OpenAlexW3162089407

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.