Evidence map›Paper›PMID 34011369›Full record

ArticleHealth and quality of life outcomes2021

The influence of hypoglycemia on the specific quality of life in type 2 diabetes mellitus: a comparative cross-sectional study of diabetics with and without hypoglycemia in Xi'an, China.

Chao Wu, Yi-Ling Ge, Xin-Yan Zhang, Ming-Chao Liu, Chun-Ni Heng, Lin-Yuan Zhang, Yan-Ling Du, Shi-Zhe He, Lei Shang, Hong-Juan Lang

Open access · goldAbstract readComparative Study
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. The Current Place of DPP4 Inhibitors in the Evolving Landscape of Type 2 Diabetes Management: Is It Time to Bid Adieu?American journal of cardiovascular drugs : drugs, devices, and other interventions · 2023
    Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chao Wu *Fourth Military Medical University, Xi'an, Shanxi, China.
Yi-Ling Ge *Fourth Military Medical University, Xi'an, Shanxi, China.
Xin-Yan Zhang75Th Group Army Hospital, Kunming, Yunnan, China.
Ming-Chao LiuFourth Military Medical University, Xi'an, Shanxi, China.
Chun-Ni HengTang Du Hospital of Fourth Military Medical University, Xi'an, Shanxi, China.
Lin-Yuan ZhangFourth Military Medical University, Xi'an, Shanxi, China.
Yan-Ling DuFourth Military Medical University, Xi'an, Shanxi, China.
Shi-Zhe HeFourth Military Medical University, Xi'an, Shanxi, China.
Lei ShangFourth Military Medical University, Xi'an, Shanxi, China. Shanglei@fmmu.edu.cn.
Hong-Juan LangFourth Military Medical University, Xi'an, Shanxi, China. Langhj@fmmu.edu.cn.ORCID http://orcid.org/0000-0002-4761-024X
Air Force Medical University · CNKunming General Hospital of Chengdu Military Command · CNTang Du Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to explore the incidence of hypoglycemia in patients with type 2 diabetes mellitus (T2DM) and the influence of hypoglycemia on the specific quality of life in T2DM patients.

methodsIt was a comparative cross-sectional study consisting of 519 T2DM patients in Xi'an, China and patients were investigated by self-reported hypoglycemia and specific quality of life questionnaires from September 2019 to January 2020. Descriptive analysis, t-test, Chi-square test, hierarchical regression analysis and stepwise multiple regression analysis were applied to assess the influence of hypoglycemia on the specific quality of life.

resultsThe incidence of hypoglycemia in T2DM patients was 32.18%. The mean score of specific quality of life in diabetes without hypoglycemia was 57.33 ± 15.36 and was 61.56 ± 17.50 in those with hypoglycemia, which indicated that hypoglycemia had a serious impact on the quality of life of diabetics (t = - 5.172, p = 0.000). In the Univariate analysis of specific quality of life, age, education background, marital status, living status, duration of diabetes, monthly income per capita were independent and significant factors associated with specific quality of life of two groups of T2DM patients (p < 0.05). In the hierarchical regression analysis, the duration of the diabetes more than 11 years and the frequency of hypoglycemia more than 6 times in half a year entered the equation of specific quality of life of 519 diabetics respectively (p < 0.001). In multiple linear regression analysis, age, marital status and income all entered the regression equation of quality of life of the two groups (p < 0.05).

conclusionHypoglycemia will have a serious impact on the quality of life of T2DM patients. In order to improve the living quality in diabetics, effective measurements should be taken to strengthen the management of blood glucose and to avoid hypoglycemia.

Indexed as

ComorbidityAdultAgedAged, 80 and overBlood GlucoseChinaCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleHumansHypoglycemiaIncidenceMaleMiddle AgedQuality of LifeRegression AnalysisBlood GlucoseChinaHypoglycemiaInfluence factorSpecific quality of lifeType 2 diabetes mellitus

Identifiers

PMID34011369
PMCPMC8136059
OpenAlexW3129887845

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.