Evidence map›Paper›PMID 34011361›Full record

ArticleHealth and quality of life outcomes2021

Predictors for quality of life improvement after surgery for degenerative cervical myelopathy: a prospective multi-center study.

Hiroyuki Inose, Takashi Hirai, Toshitaka Yoshii, Atsushi Kimura, Katsushi Takeshita, Hirokazu Inoue, Asato Maekawa, Kenji Endo, Takuya Miyamoto, Takeo Furuya and 7 more

Abstract readMulticenter Study
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hiroyuki InoseDepartment of Orthopaedic and Trauma Research, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. inose.orth@tmd.ac.jp.ORCID http://orcid.org/0000-0003-4195-2545
Takashi HiraiDepartment of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-Ku, Japan.
Toshitaka YoshiiDepartment of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-Ku, Japan.
Atsushi KimuraDepartment of Orthopaedics, Jichi Medical University, Shimotsuke, Japan.
Katsushi TakeshitaDepartment of Orthopaedics, Jichi Medical University, Shimotsuke, Japan.
Hirokazu InoueDepartment of Orthopaedics, Jichi Medical University, Shimotsuke, Japan.
Asato MaekawaDepartment of Orthopaedic Surgery, Tokyo Medical University, Shinjuku-Ku, Japan.
Kenji EndoDepartment of Orthopaedic Surgery, Tokyo Medical University, Shinjuku-Ku, Japan.
Takuya MiyamotoDepartment of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba-shi, Japan.
Takeo FuruyaDepartment of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba-shi, Japan.
Akira NakamuraDepartment of Orthopaedic Surgery, Shiga University of Medical Science, Otsu, Japan.
Kanji MoriDepartment of Orthopaedic Surgery, Shiga University of Medical Science, Otsu, Japan.
Shunsuke KanbaraDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shiro ImagamaDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shoji SekiDepartment of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan.
Shunji MatsunagaDepartment of Orthopedic Surgery, Imakiire General Hospital, Kagoshima-shi, Japan.
Atsushi OkawaDepartment of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-Ku, Japan.

Funding

the Japanese Health and Labor Sciences Research Grant. 201911033B
6 · The paper itself

Abstract

backgroundDegenerative cervical myelopathy (DCM) can significantly impair a patient's quality of life (QOL). In this study, we aimed to identify predictors associated with QOL improvement after surgery for DCM.

methodsThis study included 148 patients who underwent surgery for DCM. The European QOL-5 Dimension (EQ-5D) score, the Japanese Orthopedic Association for the assessment of cervical myelopathy (C-JOA) score, and the Nurick grade were used as outcome measures. Radiographic examinations were performed at enrollment. The associations of baseline variables with changes in EQ-5D scores from preoperative to 1-year postoperative assessment were investigated using a multivariable linear regression model.

resultsThe EQ-5D and C-JOA scores and the Nurick grade improved after surgery (P < 0.001, P < 0.001, and P < 0.001, respectively). Univariable analysis revealed that preoperative EQ-5D and C-JOA scores were significantly associated with increased EQ-5D scores from preoperative assessment to 1 year after surgery (P < 0.0001 and P = 0.045). Multivariable regression analysis showed that the independent preoperative predictors of change in QOL were lumbar lordosis (LL), sacral slope (SS), and T1 pelvic angle (TPA). According to the prediction model, the increased EQ-5D score from preoperatively to 1 year after surgery = 0.308 - 0.493 × EQ-5D + 0.006 × LL - 0.008 × SS + 0.004 × TPA.

conclusionsPreoperative LL, SS, and TPA significantly impacted the QOL of patients who underwent surgery for DCM. Less improvement in QOL after surgery was achieved in patients with smaller LL and TPA and larger SS values. Patients with these risk factors may therefore require additional support to experience adequate improvement in QOL.

Indexed as

AgedCervical VertebraeFemaleForecastingHumansJapanMaleMiddle AgedOutcome Assessment, Health CarePostoperative PeriodProspective StudiesQuality of LifeSpinal Cord DiseasesSurgical Procedures, OperativeTreatment OutcomeDegenerative cervical myelopathyEuropean QOL-5 DimensionsLumbar lordosisQuality of lifeSacral slopeSpinal cord compressionSurgeryT1 pelvic angle

Identifiers

PMID34011361
PMCPMC8132343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.