SynthesisBMC geriatrics2021
Clinical features and outcomes of COVID-19 in older adults: a systematic review and meta-analysis.
Synthesis in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 3 syntheses or guidelines pooled it, 137 citations in OpenAlex.
- Clinical expressions, characteristics and treatments of confirmed COVID-19 in nursing home residents: a systematic review.BMC geriatrics · 2023Pooled it
- The impact of the COVID-19 pandemic on mortality in people with dementia without COVID-19: a systematic review and meta-analysis.BMC geriatrics · 2022Pooled it
- Comorbidities and complications of COVID-19 associated with disease severity, progression, and mortality in China with centralized isolation and hospitalization: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Safety, immunogenicity, and long COVID outcomes following inactivated COVID-19 vaccine boosters in elderly Chinese: a prospective cohort study.Frontiers in immunology · 2026Trial
- Effect and Tolerability of a Nutritional Supplement Based on a Synergistic Combination of β-Glucans and Selenium- and Zinc-EnrichedNutrients · 2021Trial
- Seasonal dynamics and burden of respiratory syncytial virus, influenza, and COVID-19 in Brazil: a national surveillance study (2019-2023).Journal of global health · 2026Observational
- Risk Factors and Vaccination Dose Associated with COVID-19 Mortality: A Population-Based Study in Gyeongsangbuk-do, South Korea.Pathogens (Basel, Switzerland) · 2026Article
- Global vaccine development.Nature medicine · 2026Review
- The neutrophil-to-lymphocyte ratio as a marker of immunosenescence and COVID-19 outcomes in the elderly: A narrative review.Physiological reports · 2026Review
- Perceptions of care quality and human rights in Italian outpatient facilities during and after the pandemic.Frontiers in public health · 2026Article
- Vocational factors and mental health during the COVID-19 pandemic in middle-aged and older adults: longitudinal evidence from a population-based cohort.Frontiers in public health · 2026Article
- Global research trends of immunosenescence and immunotherapy: A bibliometric study.Human vaccines & immunotherapeutics · 2025Review
- Long term health related quality of life among individuals after COVID 19 recovery in a multicentric community based study.Scientific reports · 2025Article
- COVID-19 Transmission Potential and Non-Pharmaceutical Interventions in Maine During the COVID-19 Pandemic.Pathogens (Basel, Switzerland) · 2025Article
- Viral sepsis-induced mortality of older patients infected by the Omicron subvariant BA.5 of SARS-CoV-2: a retrospective study.BMC infectious diseases · 2025Article
- Longitudinal analysis of Covid-19 infection trends and in-hospital mortality across six pandemic waves in Tunisia.Archives of public health = Archives belges de sante publique · 2025Article
- Resilience Amidst Adversity: Experiences of Black Older Adults During the COVID-19 Pandemic.The Gerontologist · 2025Article
- The ZNF717-rs2918520 genotype contributes to COVID-19 severity: a Taiwanese cohort study.BMC infectious diseases · 2025Article
- Dependence in Activities of Daily Living as a Predictor of In-Hospital Mortality During COVID-19 in Older Individuals.Life (Basel, Switzerland) · 2025Article
- Effect of individual and provincial levels on stress among general population during the COVID-19 pandemic: a multilevel analysis using mental health survey in Thailand.Frontiers in public health · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have focused on exploring the clinical characteristics and outcomes of COVID-19 in older patients. We conducted this systematic review and meta-analysis to have a better understanding of the clinical characteristics of older COVID-19 patients.
methodsA systematic search of PubMed and Scopus was performed from December 2019 to May 3rd, 2020. Observational studies including older adults (age ≥ 60 years) with COVID-19 infection and reporting clinical characteristics or outcome were included. Primary outcome was assessing weighted pooled prevalence (WPP) of severity and outcomes. Secondary outcomes were clinical features including comorbidities and need of respiratory support.
resultForty-six studies with 13,624 older patients were included. Severe infection was seen in 51% (95% CI- 36-65%, I
conclusionApproximately half of older patients with COVID-19 have severe infection, one in five are critically ill and one in ten die. More high-quality evidence is needed to study outcomes in this vulnerable patient population and factors affecting these outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.