Evidence map›Paper›PMID 34011265›Full record

Observational studyBMC cardiovascular disorders2021

The relationship between the atherogenic index of plasma and arterial stiffness in essential hypertensive patients from China: a cross-sectional study.

Juan Yin, Minghui Li, Lingling Yu, Feng Hu, Yu Yu, Longlong Hu, Huihui Bao, Xiaoshu Cheng

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Juan YinDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Minghui LiDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Lingling YuDepartment of Rehabilitation, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Feng HuDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Yu YuDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Longlong HuDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Huihui BaoDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China.
Xiaoshu ChengDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang, 330006, China. xiaoshumenfan126@163.com.ORCID 0000-0001-7445-1988
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe atherogenic index of plasma (AIP) always remains in a potential association with arterial stiffness, however, this association has not been fully discovered and needs to be studied in depth in large hypertensive patient populations. The present analysis thus sought to further explore the association that exists between AIP and arterial stiffness in Chinese patients diagnosed with arterial hypertension.

methodsThis cross-sectional study analyzed 4744 Chinese individuals with essential hypertension. AIP was defined as the base 10 logarithm of the ratio of plasma of triglycerides to high-density lipoprotein cholesterol levels indicated in molar concentrations. Measurement of arterial stiffness was carried out via brachial-ankle pulse wave velocity (baPWV).

resultsData were adjusted for potential confounding variables, and multivariate linear regression analysis revealed AIP to be positively correlated with baPWV (β = 1.34, 95% CI: 0.96 to 1.72, P < 0.001). When AIP was instead treated as a categorical variable divided into quartiles, the same relationship was observed (P for trend < 0.001). We additionally found AIP and baPWV had a stronger positive association in individuals with a body mass index (BMI) < 24 kg/m

conclusionAIP and arterial stiffness were positively correlated in essential hypertension patients in China, especially in those with a BMI < 24 kg/m

Indexed as

Arterial PressureVascular StiffnessAdultAgedAged, 80 and overBiomarkersBody Mass IndexChinaCholesterol, HDLCross-Sectional StudiesDyslipidemiasEssential HypertensionFemaleHumansMaleMiddle AgedBiomarkersCholesterol, HDLTriglyceridesArterial stiffnessAtherogenic index of plasmaBrachial-ankle pulse wave velocityHypertension

Identifiers

PMID34011265
PMCPMC8136204
OpenAlexW3127680815

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.