Evidence map›Paper›PMID 34010940›Full record

ReviewPain2022

Framework for opioid stigma in cancer pain.

Hailey W Bulls, Edward Chu, Burel R Goodin, Jane M Liebschutz, Antoinette Wozniak, Yael Schenker, Jessica S Merlin

Open access · greenAbstract readReview
In one paragraph

Review in Pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Opioid consumption, availability, and policy alignment in primary hospice and palliative care in China: a multicomponent comparative analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  3. Article
  4. Article
  5. Review
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  7. Article
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  9. Article
  10. Lifetime Pain Management Experiences of Female Breast Cancer Survivors Aged 65+ Years.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2025
    Article
  11. Article
  12. Review
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  14. Review
  15. Article
  16. Article
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  18. Pain, depressive symptoms, and self-efficacy for pain management: examination in African-American women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hailey W BullsSection of Palliative Care and Medical Ethics and Palliative Research Center (PaRC), Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-1005-0303
Edward ChuDepartment of Medicine & Molecular Pharmacology, Albert Einsten Cancer Center, Albert Einstein College of Medicine, Bronx, NY, United States.
Burel R GoodinDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0002-8159-1310
Jane M LiebschutzDivision of General Internal Medicine, Center for Research on Health Care, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-3492-1521
Antoinette WozniakDivision of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Yael SchenkerSection of Palliative Care and Medical Ethics and Palliative Research Center (PaRC), Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-1307-9988
Jessica S MerlinSection of Palliative Care and Medical Ethics and Palliative Research Center (PaRC), Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
University of Pittsburgh · USAlbert Einstein College of Medicine · USUniversity of Alabama at Birmingham · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0M
Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
Project-008UG1DA049436 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jane M. Liebschutz, Erin L Winstanley · 2019 to 2026
$10.5M
Midcareer Investigator Award in Patient-Oriented Research: Yael Schenker, MD, MASK24AG070285 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHENKER, YAEL · 2021 to 2025
$841k
NCATS NIH HHS KL2 TR001856NCI NIH HHS P30 CA047904NIA NIH HHS K24 AG070285NIDA NIH HHS UG1 DA049436
6 · The paper itself

Abstract

abstractMillions of patients with cancer pain are treated with prescription opioids each year. However, efforts to mitigate the ongoing opioid crisis result in unintended consequences with opioid pain management, including opioid stigma. Emerging research indicates that opioid stigma is problematic in patients with cancer, but few studies have examined contributors to and impacts of opioid stigma in this population. To guide future research in this area, we propose a conceptual framework-the opioid stigma framework (OSF)-with which to understand and improve opioid stigma in patients with cancer pain. Development of the OSF was guided by a literature review of stigma in health-related conditions, adaptation of the existing Health Stigma and Discrimination Framework, a topical review of challenges related to opioid cancer pain management, and author expertise in cancer, pain, and opioid prescribing. The proposed OSF highlights 5 domains: (1) contributors to opioid stigma, or factors that increase the likelihood that a patient will experience opioid stigma; (2) intersecting stigmas, or the convergence of multiple stigmatized identities within a patient; (3) stigma manifestations, or the ways opioid stigma is manifested in patients, clinicians, and the community; (4) proximal outcomes, or the immediate consequences of opioid stigma in patients; and (5) long-term impacts in patients. The OSF provides 2 main avenues to facilitate future research: (1) providing a framework to explore the mechanisms that underlie opioid stigma and its impact on cancer pain management and (2) supporting the development of targeted, tailored interventions to eliminate opioid stigma.

Indexed as

Cancer PainNeoplasmsAnalgesics, OpioidHumansPainPain ManagementPractice Patterns, Physicians'Analgesics, Opioid

Identifiers

PMID34010940
PMCPMC8589872
OpenAlexW3161670301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.