Evidence map›Paper›PMID 34010618›Full record

ArticleEuropean journal of pharmacology2021

Antitussive effects of Na

Li Yu, Kojun Tsuji, Izumi Ujihara, Qi Liu, Nikoleta Pavelkova, Takanori Tsujimura, Makoto Inoue, Sonya Meeker, Eric Nisenbaum, Jeff S McDermott and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Role of NaThe Journal of physiology · 2024
    Article
  3. Review
  4. Inhibition of NaRSC medicinal chemistry · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Li YuDepartment of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongii University School of Medicine, Shanghai, 200065, China.
Kojun TsujiDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Izumi UjiharaDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Qi LiuJohns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD, 21224, USA.
Nikoleta PavelkovaMolecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Takanori TsujimuraDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Makoto InoueDivision of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Sonya MeekerJohns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD, 21224, USA.
Eric NisenbaumLilly Research Laboratories, Indianapolis, IN, 46285, USA.
Jeff S McDermottLilly Research Laboratories, Indianapolis, IN, 46285, USA.
Jeff KrajewskiLilly Research Laboratories, Indianapolis, IN, 46285, USA.
Bradley J UndemJohns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD, 21224, USA.
Marian KollarikMolecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Brendan J CanningJohns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD, 21224, USA. Electronic address: bjc@jhmi.edu.
Johns Hopkins University · USNiigata University · JPEli Lilly (United States) · USUniversity of South Florida · USTongji University · CN

Funding

Neurobiology of the Bronchopulmonary SystemR35HL155671 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Bradley Joel Undem · 2021 to 2026
$5.6M
Control of Airway Sensory Nerve Function by Voltage-Gated Sodium Channel SubtypesR01HL122228 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI UNDEM, BRADLEY JOEL · 2014 to 2020
$3.2M
NHLBI NIH HHS R01 HL122228NHLBI NIH HHS R35 HL155671
6 · The paper itself

Abstract

Our previous studies implicated the voltage-gated sodium channel subtype Na

Indexed as

Antitussive AgentsCoughNAV1.7 Voltage-Gated Sodium ChannelVagus NerveAction PotentialsAmbroxolAnimalsCitric AcidDose-Response Relationship, DrugGuinea PigsHumansMaleVoltage-Gated Sodium Channel BlockersAmbroxolAntitussive AgentsCitric AcidNAV1.7 Voltage-Gated Sodium ChannelVoltage-Gated Sodium Channel BlockersAmbroxolCardiovascularPainRespiratorySodium channelVagal

Identifiers

PMID34010618
PMCPMC11822864
OpenAlexW3162837521

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.