Evidence map›Paper›PMID 34010350›Full record

ArticlePloS one2021

Accuracy of autorefraction in an adult Indian population.

Rajesh S Kumar, Caitlin A Moe, Deepak Kumar, Mahalakshmi V Rackenchath, Sathi Devi A V, Sriharsha Nagaraj, Dionna M Wittberg, Robert L Stamper, Jeremy D Keenan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Assessment of the Spot vision screener performance in detecting amblyopia and strabismus in Nepal: a prospective diagnostic accuracy study.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. What are the causes of non-tolerance to new spectacles and how can they be avoided?Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rajesh S KumarNarayana Nethralaya Eye Hospital, Bangalore, India.ORCID 0000-0002-5296-6267
Caitlin A MoeFrancis I Proctor Foundation, University of California, San Francisco, San Francisco, CA, United States of America.
Deepak KumarNarayana Nethralaya Eye Hospital, Bangalore, India.
Mahalakshmi V RackenchathNarayana Nethralaya Eye Hospital, Bangalore, India.
Sathi Devi A VNarayana Nethralaya Eye Hospital, Bangalore, India.
Sriharsha NagarajNarayana Nethralaya Eye Hospital, Bangalore, India.
Dionna M WittbergFrancis I Proctor Foundation, University of California, San Francisco, San Francisco, CA, United States of America.
Robert L StamperDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, United States of America.
Jeremy D KeenanFrancis I Proctor Foundation, University of California, San Francisco, San Francisco, CA, United States of America.ORCID 0000-0002-7118-1457
Narayana Nethralaya · INUniversity of California, San Francisco · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAutorefractors allow non-specialists to quickly assess refractive error, and thus could be a useful component of large-scale vision screening programs. In order to better characterize the role of autorefraction for public health outreach programs in resource-limited settings, the diagnostic accuracy of two autorefractors was assessed relative to subjective refraction in an adult Indian population.

methodsAn optometrist refracted a series of patients aged ≥50 years at an eye clinic in Bangalore, India using the Nidek ARK-900 autorefractor first, followed by the 3nethra Royal autorefractor, and then subjective refraction. The diagnostic accuracy of each autorefractor for myopia, hyperopia, and astigmatism was assessed using subjective refraction as the reference standard, and measures of agreement between refractions were calculated.

resultsA total of 197 eyes in 104 individuals (mean age 63 ± 8 years, 52% female) were evaluated. Both autorefractors produced spherical equivalent estimates that were on average more hyperopic than subjective refraction, with a measurement bias of +0.16 D (95%CI +0.09 to +0.23D) for Nidek and +0.42 D (95%CI +0.28 to +0.54D) for 3nethra. When comparing pairs of measurements from autorefraction and subjective refraction, the limits of agreement were approximately ±1D for the Nidek autorefractor and ±1.75D for the 3Nethra autorefractor. The sensitivity and specificity of detecting ≥1 diopter of myopia were 94.6% (95%CI 86.8-100%) and 92.5% (95%CI 88.9-97.5%) for the Nidek, and 89.2% (95%CI 66.7-97.4) and 77.5% (95%CI 71.2-99.4%) for the 3Nethra. The accuracy of each autorefractor increased at greater levels of refractive error.

conclusionsThe sensitivity and specificity of the Nidek autorefractor for diagnosing refractive error among adults ≥50 years in an urban Indian clinic was sufficient for screening for visually significant refractive errors, although the relatively wide limits of agreement suggest that subjective refinement of the eyeglasses prescription would still be necessary.

Indexed as

AgedAstigmatismFemaleHumansHyperopiaIndiaMaleMiddle AgedMyopiaProspective StudiesRefraction, OcularRefractive ErrorsVision Screening

Identifiers

PMID34010350
PMCPMC8133404
OpenAlexW3163825278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.