Evidence map›Paper›PMID 34009996›Full record

ArticleThe journal of physical chemistry. A2021

Extraction of Weak Spectroscopic Signals with High Fidelity: Examples from ESR.

Madhur Srivastava, Boris Dzikovski, Jack H Freed

Abstract read
In one paragraph

Article in The journal of physical chemistry. A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Optimal Wavelet Selection for Signal Denoising.IEEE access : practical innovations, open solutions · 2024
    Article
  3. Article
  4. Article
  5. Analysis of Small-Molecule Mixtures by Super-ResolvedThe journal of physical chemistry. A · 2022
    Article
  6. Hyperfine Decoupling of ESR Spectra Using Wavelet Transform.Magnetochemistry (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madhur SrivastavaDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca 14853, United States.ORCID https://orcid.org/0000-0002-2095-0412
Boris DzikovskiDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca 14853, United States.ORCID https://orcid.org/0000-0002-5687-5207
Jack H FreedDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca 14853, United States.ORCID https://orcid.org/0000-0003-4288-2585

Funding

TR&D 4 for ACERT, 2017-2021 funding periodP41GM103521 · NIGMS · CORNELL UNIVERSITY · PI FREED, JACK H · 2012 to 2021
$11.7M
NIGMS NIH HHS P41 GM103521
6 · The paper itself

Abstract

Noise impedes experimental studies by reducing signal resolution and/or suppressing weak signals. Signal averaging and filtering are the primary methods used to reduce noise, but they have limited effectiveness and lack capabilities to recover signals at low signal-to-noise ratios (SNRs). We utilize a wavelet transform-based approach to effectively remove noise from spectroscopic data. The wavelet denoising method we use is a significant improvement on standard wavelet denoising approaches. We demonstrate its power in extracting signals from noisy spectra on a variety of signal types ranging from hyperfine lines to overlapped peaks to weak peaks overlaid on strong ones, drawn from electron-spin-resonance spectroscopy. The results show that one can accurately extract details of complex spectra, including retrieval of very weak ones. It accurately recovers signals at an SNR of ∼1 and improves the SNR by about 3 orders of magnitude with high fidelity. Our examples show that one is now able to address weaker SNR signals much better than by previous methods. This new wavelet approach can be successfully applied to other spectroscopic signals.

Identifiers

PMID34009996
PMCPMC8317606

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.