Evidence map›Paper›PMID 34009648›Full record

ReviewExperimental dermatology2021

Wound healing applications of creams and "smart" hydrogels.

Diana Stan, Cristiana Tanase, Marioara Avram, Roxana Apetrei, Nicolae-Bogdan Mincu, Andreea Lorena Mateescu, Dana Stan

Abstract readReview
In one paragraph

Review in Experimental dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. [Role and mechanism of Wnt9a in human and mouse chronic wound healing].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026
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  18. Application ofMolecules (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diana StanDDS Diagnostic, Bucharest, Romania.ORCID 0000-0002-5741-5536
Cristiana TanaseFaculty of Medicine, Titu Maiorescu University, Bucharest, Romania.
Marioara AvramDDS Diagnostic, Bucharest, Romania.
Roxana ApetreiDDS Diagnostic, Bucharest, Romania.
Nicolae-Bogdan MincuDDS Diagnostic, Bucharest, Romania.
Andreea Lorena MateescuDDS Diagnostic, Bucharest, Romania.
Dana StanDDS Diagnostic, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although superficial wounds are often easy to treat for healthy individuals, there are some more severe types of wounds (burns, ulcers, diabetic wounds, etc.) that are a challenge for clinicians. A good therapeutic result is based on the delivery of a treatment at the right time, for the right patient. Our goal was to sum up useful knowledge regarding wound healing and wound treatments, based on creams and hydrogels with various active ingredients. We concluded that both preparations have application in preventing infections and promoting healing, but their efficacy is clearly conditioned by the type, depth, severity of the wound and patient profile. However, due to their superior versatility and capability of maintaining the integrity and functionality of the active ingredient, as well as it is controlled release at site, hydrogels are more suited for incorporating different active ingredients. New wound healing devices can combine smart hydrogel dressings with physical therapies to deliver a more efficient treatment to patients if the indications are appropriate.

Indexed as

Administration, TopicalHydrogelsSkin CreamCombined Modality TherapyHumansWound HealingHydrogelscreamssmart hydrogelswound classificationwound dressingwound healing

Identifiers

PMID34009648
PMCPMC8453519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.