Evidence map›Paper›PMID 34009632›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2021

Low-power infrared laser modulates telomere length in heart tissue from an experimental model of acute lung injury.

Larissa Alexsandra da Silva Neto Trajano, Luiz Philippe da Silva Sergio, Diego Sá Leal de Oliveira, Eduardo Tavares Lima Trajano, Marco Aurélio Dos Santos Silva, Flavia de Paoli, André Luiz Mencalha, Adenilson de Souza da Fonseca

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Larissa Alexsandra da Silva Neto TrajanoMestrado Profissional em Diagnóstico em Medicina Veterinária, Universidade de Vassouras. Avenida Expedicionário Oswaldo de Almeida Ramos, 280, Vassouras, , Rio de Janeiro, 27700000, Brazil. larissa.alexsandra@hotmail.com.ORCID http://orcid.org/0000-0002-2600-9770
Luiz Philippe da Silva SergioDepartamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, fundos, Vila Isabel, Rio de Janeiro, 20551030, Brazil.
Diego Sá Leal de OliveiraDepartamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, fundos, Vila Isabel, Rio de Janeiro, 20551030, Brazil.
Eduardo Tavares Lima TrajanoMestrado Profissional em Ciências Aplicadas em Saúde, Universidade de Vassouras, Avenida Expedicionário Oswaldo de Almeida Ramos, 280, Vassouras, Rio de Janeiro, 27700000, Brazil.
Marco Aurélio Dos Santos SilvaMestrado Profissional em Ciências Aplicadas em Saúde, Universidade de Vassouras, Avenida Expedicionário Oswaldo de Almeida Ramos, 280, Vassouras, Rio de Janeiro, 27700000, Brazil.
Flavia de PaoliDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Minas Gerais, Rua José Lourenço Khelmer - s/n, Campus Universitário, São Pedro, Juiz de Fora, 36036900, Brazil.
André Luiz MencalhaDepartamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, fundos, Vila Isabel, Rio de Janeiro, 20551030, Brazil.
Adenilson de Souza da FonsecaDepartamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, fundos, Vila Isabel, Rio de Janeiro, 20551030, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury and acute respiratory distress syndrome can occur as a result of sepsis. Cardiac dysfunction is a serious component of multi-organ failure caused by severe sepsis. Telomere shortening is related to several heart diseases. Telomeres are associated with the shelterin protein complex, which contributes to the maintenance of telomere length. Low-power infrared lasers modulate mRNA levels of shelterin complex genes. This study aimed to evaluate effects of a low-power infrared laser on mRNA relative levels of genes involved in telomere stabilization and telomere length in heart tissue of an experimental model of acute lung injury caused by sepsis. Animals were divided into six groups, treated with intraperitoneal saline solution, saline solution and exposed to a low-power infrared laser at 10 J cm

Indexed as

HeartLasersAcute Lung InjuryAnimalsLipopolysaccharidesRNA, MessengerSepsisTelomereLipopolysaccharidesRNA, MessengerLow-power laserTelomeraseTelomere length

Identifiers

PMID34009632
PMCPMC8131880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.