Evidence map›Paper›PMID 34009506›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2021

The effect of negative pressure wound therapy on surgical site occurrences in closed incision abdominal wall reconstructions: a retrospective single surgeon and institution study.

A P Seaman, B A Sarac, H ElHawary, J E Janis

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05455801 (Randomized Study on the Efficacy of Negative Pressure Wound Therapy), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05455801 nacompletednot on this map

Randomized Study on the Efficacy of Negative Pressure Wound Therapy (NPWT) in the Prevention of Surgical Site Complications

TypeinterventionalSponsorHospital Universitario Central de AsturiasRan2019 to 2021Enrolled271ConditionsSurgical Site Infection, Complication,Postoperative, Surgical Wound Infection, Surgical ComplicationArmsnegative preassure wound therapy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Association between surgical hernia repair techniques and the incidence of seroma-Authors' reply.Hernia : the journal of hernias and abdominal wall surgery · 2022
    Article
  7. Building a Center for Abdominal Core Health: The Importance of a Holistic Multidisciplinary Approach.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

A P SeamanCollege of Medicine, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-3454-268X
B A SaracDepartment of Plastic and Reconstructive Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road, Suite 2100, Columbus, OH, 43212, USA.ORCID http://orcid.org/0000-0001-7825-4957
H ElHawaryDivision of Plastic and Reconstructive Surgery, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0003-4542-5814
J E JanisDepartment of Plastic and Reconstructive Surgery, The Ohio State University Wexner Medical Center, 915 Olentangy River Road, Suite 2100, Columbus, OH, 43212, USA. Jeffrey.janis@osumc.edu.ORCID http://orcid.org/0000-0001-6103-4798
The Ohio State University Wexner Medical Center · USMcGill University · CAThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe use of closed incision negative pressure wound therapy (ciNPWT) in abdominal wall reconstruction is heavily debated. The current literature shows mixed results for its efficacy in preventing surgical site occurrences (SSOs), and many of the studies are limited by small sample size or a lack of generalizability. We sought to assess whether the use of prophylactic ciNPWT has an effect on reducing the rate of SSOs.

methodsFollowing institutional review board approval, a retrospective analysis of a prospectively collected abdominal wall reconstruction database of a single surgeon at a single institution was completed. Two hundred and seventy patients were reviewed. Univariate and multivariate logistic regressions were performed to assess the effect of each variable on the rate of SSOs.

resultsTwo hundred and fifty-eight patients (95.56%) met inclusion criteria. One hundred and fifty-nine (61.63%) of these patients received ciNPWT. The median duration of ciNPWT was 6 days. Multivariate logistic regression analysis showed no significant difference in the prevalence of SSOs between groups (OR = 0.843, 95% CI [0.445-1.594], p = 0.598). It did, however, show a significant decrease in the rates of seroma (7.07% vs. 0.63%, p = 0.004). Moreover, skin resection was associated with a decreased rate of SSO (OR = 0.295, 95% CI [0.096-0.911], p = 0.034).

conclusionsciNPWT was not associated with a decrease in SSOs following abdominal wall reconstruction but did show a statistically significant decrease in postoperative seromas. Future, large prospective analyses may help further discover the utility of ciNPWT in reducing SSOs.

Indexed as

Abdominal WallNegative-Pressure Wound TherapySurgical WoundHerniorrhaphyHumansRetrospective StudiesSurgical Wound InfectionClosed incision negative pressure wound therapy

Identifiers

PMID34009506
OpenAlexW3163665865

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.